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Oxytrodiflavanone A and Oxytrochalcoflavanones A,B: New Biflavonoids from Oxytropis chiliophylla.
Liu, Yang; Kelsang, Norbo; Lu, Jianghai; Zhang, Yingtao; Liang, Hong; Tu, Pengfei; Kong, Dexin; Zhang, Qingying.
Afiliación
  • Liu Y; State Key Laboratory of Natural and Biomimetic Drugs and Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China. 1311210122@bjmu.edu.cn.
  • Kelsang N; State Key Laboratory of Natural and Biomimetic Drugs and Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China. kelsang815@163.com.
  • Lu J; National Anti-Doping Laboratory, China Anti-Doping Agency, Beijing 100029, China. lujianghai@chinada.cn.
  • Zhang Y; State Key Laboratory of Natural and Biomimetic Drugs and Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China. zytao1988@163.com.
  • Liang H; State Key Laboratory of Natural and Biomimetic Drugs and Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China. lianghong@bjmu.edu.cn.
  • Tu P; State Key Laboratory of Natural and Biomimetic Drugs and Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China. pengfeitu@bjmu.edu.cn.
  • Kong D; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin 300070, China. kongdexin@tmu.edu.cn.
  • Zhang Q; Research Center, School of Medicine, Tianjin Tianshi College, Tianyuan University, Tianjin 301700, China. kongdexin@tmu.edu.cn.
Molecules ; 24(8)2019 Apr 13.
Article en En | MEDLINE | ID: mdl-31013944
ABSTRACT
Three previously undescribed biflavonoids, oxytrodiflavanone A (1), and oxytrochalcoflavanones A,B (2,3), were isolated from the aerial part of Oxytropis chiliophylla, together with their putative biosynthetic monomers, i.e., (2S)-5,7-dihydroxyflavanone (4), (2S)-7-hydroxyflavanone (5), and 2',4'-dihydroxychalcone (6). The structures of these compounds were elucidated by a combination analysis of spectroscopic data. The cytotoxic activities of all the isolated compounds against PC-3 human prostate cancer cell line are also presented.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Oxytropis / Biflavonoides / Flavanonas / Chalconas / Antineoplásicos Fitogénicos Límite: Humans / Male Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Oxytropis / Biflavonoides / Flavanonas / Chalconas / Antineoplásicos Fitogénicos Límite: Humans / Male Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China