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Structure of a Therapeutic Full-Length Anti-NPRA IgG4 Antibody: Dissecting Conformational Diversity.
Blech, Michaela; Hörer, Stefan; Kuhn, Alexander B; Kube, Sebastian; Göddeke, Hendrik; Kiefer, Hans; Zang, Yuguo; Alber, Yannic; Kast, Stefan M; Westermann, Martin; Tully, Mark D; Schäfer, Lars V; Garidel, Patrick.
Afiliación
  • Blech M; Innovation Unit, Pharmaceutical Development Biologics, Biberach (Riss), Germany. Electronic address: michaela.blech@boehringer-ingelheim.com.
  • Hörer S; Department Lead Identification and Optimization Support, Structural Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach (Riss), Germany.
  • Kuhn AB; Theoretical Chemistry, Ruhr University Bochum, Bochum, Germany.
  • Kube S; Innovation Unit, Pharmaceutical Development Biologics, Biberach (Riss), Germany.
  • Göddeke H; Theoretical Chemistry, Ruhr University Bochum, Bochum, Germany.
  • Kiefer H; University of Applied Sciences Biberach, Biberach (Riss), Germany.
  • Zang Y; University of Applied Sciences Biberach, Biberach (Riss), Germany.
  • Alber Y; Physikalische Chemie III, Technische Universität Dortmund, Dortmund, Germany.
  • Kast SM; Physikalische Chemie III, Technische Universität Dortmund, Dortmund, Germany.
  • Westermann M; Elektronenmikroskopisches Zentrum, Friedrich-Schiller-Universität Jena, Jena, Germany.
  • Tully MD; European Synchrotron Radiation Facility, Grenoble, France.
  • Schäfer LV; Theoretical Chemistry, Ruhr University Bochum, Bochum, Germany.
  • Garidel P; Innovation Unit, Pharmaceutical Development Biologics, Biberach (Riss), Germany. Electronic address: patrick.garidel@boehringer-ingelheim.com.
Biophys J ; 116(9): 1637-1649, 2019 05 07.
Article en En | MEDLINE | ID: mdl-31023536
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inmunoglobulina G / Receptores del Factor Natriurético Atrial / Anticuerpos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Biophys J Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inmunoglobulina G / Receptores del Factor Natriurético Atrial / Anticuerpos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Biophys J Año: 2019 Tipo del documento: Article