An enhancer factor defect in a mutant Burkitt lymphoma cell line.
J Exp Med
; 167(6): 1781-90, 1988 Jun 01.
Article
en En
| MEDLINE
| ID: mdl-3133441
ABSTRACT
RJ 2.2.5 is an immunoselected mutant of the Burkitt lymphoma line Raji. It fails to display MHC class II antigens at the cell surface due to a transcriptional defect. We have identified the function of a regulatory factor that is defective in RJ 2.2.5 cells; this factor is absolutely required for the activity of an MHC class II gene enhancer.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Antígenos HLA-D
/
Elementos de Facilitación Genéticos
/
Genes MHC Clase II
/
Proteínas de Unión al ADN
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
J Exp Med
Año:
1988
Tipo del documento:
Article