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Thiohydantoin derivatives incorporating a pyrazole core: Design, synthesis and biological evaluation as dual inhibitors of topoisomerase-I and cycloxygenase-2 with anti-cancer and anti-inflammatory activities.
Abdellatif, Khaled R A; Fadaly, Wael A A; Mostafa, Yaser A; Zaher, Dana M; Omar, Hany A.
Afiliación
  • Abdellatif KRA; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt. Electronic address: khaled.ahmed@pharm.bsu.edu.eg.
  • Fadaly WAA; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt.
  • Mostafa YA; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut 71515, Egypt.
  • Zaher DM; Sharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates.
  • Omar HA; Sharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates; Department of Pharmacology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt.
Bioorg Chem ; 91: 103132, 2019 10.
Article en En | MEDLINE | ID: mdl-31374529
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirazoles / Tiohidantoínas / Inhibidores Enzimáticos / Antiinflamatorios / Antineoplásicos Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirazoles / Tiohidantoínas / Inhibidores Enzimáticos / Antiinflamatorios / Antineoplásicos Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2019 Tipo del documento: Article