Inhibiting nucleolin reduces inflammation induced by mitochondrial DNA in cardiomyocytes exposed to hypoxia and reoxygenation.

Mariero, Lars Henrik; Torp, May-Kristin; Heiestad, Christina Mathisen; Baysa, Anton; Li, Yuchuan; Valen, Guro; Vaage, Jarle; Stensløkken, Kåre-Olav

Mariero, Lars Henrik; Torp, May-Kristin; Heiestad, Christina Mathisen; Baysa, Anton; Li, Yuchuan; Valen, Guro; Vaage, Jarle; Stensløkken, Kåre-Olav.

Afiliación

Mariero LH; Department of Molecular Medicine, Division of Physiology, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway.
Torp MK; Center for Heart Failure Research, Faculty of Medicine, University of Oslo, Oslo, Norway.
Heiestad CM; Department of Molecular Medicine, Division of Physiology, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway.
Baysa A; Center for Heart Failure Research, Faculty of Medicine, University of Oslo, Oslo, Norway.
Li Y; Department of Molecular Medicine, Division of Physiology, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway.
Valen G; Center for Heart Failure Research, Faculty of Medicine, University of Oslo, Oslo, Norway.
Vaage J; Department of Molecular Medicine, Division of Physiology, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway.
Stensløkken KO; Center for Heart Failure Research, Faculty of Medicine, University of Oslo, Oslo, Norway.

Br J Pharmacol ; 176(22): 4360-4372, 2019 11.

Article en En | MEDLINE | ID: mdl-31412132

Asunto(s)

ADN/metabolismo; Hipoxia/metabolismo; Miocitos Cardíacos/metabolismo; Fosfoproteínas/metabolismo; Proteínas de Unión al ARN/metabolismo; Animales; Islas de CpG; Fibroblastos/metabolismo; Células HEK293; Humanos; Inflamación/genética; Inflamación/metabolismo; Masculino; Ratones Endogámicos C57BL; FN-kappa B/metabolismo; Oxígeno/farmacología; Fosfoproteínas/genética; Proteínas de Unión al ARN/genética; Receptor Toll-Like 9/genética; Receptor Toll-Like 9/metabolismo; Nucleolina

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fosfoproteínas / ADN / Proteínas de Unión al ARN / Miocitos Cardíacos / Hipoxia Límite: Animals / Humans / Male Idioma: En Revista: Br J Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: Noruega

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