The impact of CTLA-4 blockade and interferon-&#945; on clonality of T-cell repertoire in the tumor microenvironment and peripheral blood of metastatic melanoma patients.

Khunger, Arjun; Rytlewski, Julie A; Fields, Paul; Yusko, Erik C; Tarhini, Ahmad A

The impact of CTLA-4 blockade and interferon-α on clonality of T-cell repertoire in the tumor microenvironment and peripheral blood of metastatic melanoma patients.

Khunger, Arjun; Rytlewski, Julie A; Fields, Paul; Yusko, Erik C; Tarhini, Ahmad A.

Afiliación

Khunger A; Department of Hematology and Oncology, Cleveland Clinic, Cleveland, OH, USA.
Rytlewski JA; Adaptive Biotechnologies, Seattle, WA, USA.
Fields P; Adaptive Biotechnologies, Seattle, WA, USA.
Yusko EC; Adaptive Biotechnologies, Seattle, WA, USA.
Tarhini AA; Department of Cutaneous Oncology, Moffitt Comprehensive Cancer Center, Tampa, Florida, USA.

Oncoimmunology ; 8(11): e1652538, 2019.

Article en En | MEDLINE | ID: mdl-31646098

Palabras clave

CDR3; CTLA-4; Immune repertoire; Interferon; T-cell receptor (TCR); TCR profiling; TCR repertoire; Tremelimumab

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Clinical_trials Idioma: En Revista: Oncoimmunology Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

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