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Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer.
Fang, Hu; Barbour, Jayne A; Poulos, Rebecca C; Katainen, Riku; Aaltonen, Lauri A; Wong, Jason W H.
Afiliación
  • Fang H; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region.
  • Barbour JA; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region.
  • Poulos RC; Prince of Wales Clinical School, UNSW Medicine, UNSW Sydney, New South Wales, Australia.
  • Katainen R; Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, New South Wales, Australia.
  • Aaltonen LA; Applied Tumor Genomics Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
  • Wong JWH; Department of Medical and Clinical Genetics, Medicum, University of Helsinki, Helsinki, Finland.
PLoS Genet ; 16(2): e1008572, 2020 02.
Article en En | MEDLINE | ID: mdl-32012149
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Proteína p53 Supresora de Tumor / ADN Polimerasa II / Carcinogénesis / Dominios Proteicos / Proteínas de Unión a Poli-ADP-Ribosa Límite: Humans Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2020 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Proteína p53 Supresora de Tumor / ADN Polimerasa II / Carcinogénesis / Dominios Proteicos / Proteínas de Unión a Poli-ADP-Ribosa Límite: Humans Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2020 Tipo del documento: Article