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Venetoclax combines synergistically with FLT3 inhibition to effectively target leukemic cells in FLT3-ITD+ acute myeloid leukemia models.
Singh Mali, Raghuveer; Zhang, Qi; DeFilippis, Rosa Anna; Cavazos, Antonio; Kuruvilla, Vinitha Mary; Raman, Jayant; Mody, Vidhi; Choo, Edna F; Dail, Monique; Shah, Neil P; Konopleva, Marina; Sampath, Deepak; Lasater, Elisabeth A.
Afiliación
  • Singh Mali R; Department of Translational Oncology, Genentech, Inc., South San Francisco, CA, USA.
  • Zhang Q; Department of Leukemia, The University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
  • DeFilippis RA; Division of Hematology and Oncology, University of California at San Francisco, San Francisco, USA.
  • Cavazos A; Department of Leukemia, The University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
  • Kuruvilla VM; Department of Leukemia, The University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
  • Raman J; Division of Hematology and Oncology, University of California at San Francisco, San Francisco, USA.
  • Mody V; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA, USA.
  • Choo EF; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA, USA.
  • Dail M; Oncology Biomarker Development, Genentech, Inc., South San Francisco, CA, USA.
  • Shah NP; Helen Diller Comprehensive Cancer Center, University of California at San Francisco, USA.
  • Konopleva M; Department of Leukemia, The University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
  • Sampath D; Department of Translational Oncology, Genentech, Inc., South San Francisco, CA, USA.
  • Lasater EA; Department of Translational Oncology, Genentech, Inc., South San Francisco, CA, USA.
Haematologica ; 106(4): 1034-1046, 2021 04 01.
Article en En | MEDLINE | ID: mdl-32414851
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda Límite: Adult / Humans Idioma: En Revista: Haematologica Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda Límite: Adult / Humans Idioma: En Revista: Haematologica Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos