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Acetyl-CoA Derived from Hepatic Peroxisomal ß-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation.
He, Anyuan; Chen, Xiaowen; Tan, Min; Chen, Yali; Lu, Dongliang; Zhang, Xiangyu; Dean, John M; Razani, Babak; Lodhi, Irfan J.
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  • He A; Division of Endocrinology, Metabolism and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Chen X; Division of Endocrinology, Metabolism and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Tan M; Division of Endocrinology, Metabolism and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Chen Y; Division of Endocrinology, Metabolism and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Lu D; Division of Endocrinology, Metabolism and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Zhang X; Cardiology Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Dean JM; Division of Endocrinology, Metabolism and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Razani B; Cardiology Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Veterans Affairs St. Louis Healthcare System, John Cochran Division, St. Louis, MO 63106, USA.
  • Lodhi IJ; Division of Endocrinology, Metabolism and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: ilodhi@wustl.edu.
Mol Cell ; 79(1): 30-42.e4, 2020 07 02.
Article en En | MEDLINE | ID: mdl-32473093
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Acetilcoenzima A / Autofagia / Peroxisomas / Acil-CoA Oxidasa / Ácidos Grasos / Hígado Graso / Diana Mecanicista del Complejo 1 de la Rapamicina Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Acetilcoenzima A / Autofagia / Peroxisomas / Acil-CoA Oxidasa / Ácidos Grasos / Hígado Graso / Diana Mecanicista del Complejo 1 de la Rapamicina Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos