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3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope-specific plasma cells and humoral immunity in nonhuman primates.
Kasturi, Sudhir Pai; Rasheed, Mohammed Ata Ur; Havenar-Daughton, Colin; Pham, Mathew; Legere, Traci; Sher, Zarpheen Jinnah; Kovalenkov, Yevgeny; Gumber, Sanjeev; Huang, Jessica Y; Gottardo, Raphael; Fulp, William; Sato, Alicia; Sawant, Sheetal; Stanfield-Oakley, Sherry; Yates, Nicole; LaBranche, Celia; Alam, S Munir; Tomaras, Georgia; Ferrari, Guido; Montefiori, David; Wrammert, Jens; Villinger, Francois; Tomai, Mark; Vasilakos, John; Fox, Christopher B; Reed, Steven G; Haynes, Barton F; Crotty, Shane; Ahmed, Rafi; Pulendran, Bali.
Afiliación
  • Kasturi SP; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, 954, Gatewood Road, Atlanta, GA, USA.
  • Rasheed MAU; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, 954, Gatewood Road, Atlanta, GA, USA.
  • Havenar-Daughton C; Division of Microbiology and Immunology and Rollins Research Center, Emory University, 1510 Clifton Road, Atlanta, GA, USA.
  • Pham M; Division of Vaccine Discovery, La Jolla Institute of Immunology, La Jolla, CA, USA.
  • Legere T; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, 954, Gatewood Road, Atlanta, GA, USA.
  • Sher ZJ; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, 954, Gatewood Road, Atlanta, GA, USA.
  • Kovalenkov Y; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, 954, Gatewood Road, Atlanta, GA, USA.
  • Gumber S; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, 954, Gatewood Road, Atlanta, GA, USA.
  • Huang JY; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, 954, Gatewood Road, Atlanta, GA, USA.
  • Gottardo R; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, 954, Gatewood Road, Atlanta, GA, USA.
  • Fulp W; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Sato A; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Sawant S; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Stanfield-Oakley S; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center Durham, NC, USA.
  • Yates N; Department of Molecular Genetics and Microbiology and Department of Immunology, Duke University, NC, USA.
  • LaBranche C; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center Durham, NC, USA.
  • Alam SM; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center Durham, NC, USA.
  • Tomaras G; Department of Molecular Genetics and Microbiology and Department of Immunology, Duke University, NC, USA.
  • Ferrari G; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center Durham, NC, USA.
  • Montefiori D; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center Durham, NC, USA.
  • Wrammert J; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center Durham, NC, USA.
  • Villinger F; Department of Molecular Genetics and Microbiology and Department of Immunology, Duke University, NC, USA.
  • Tomai M; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center Durham, NC, USA.
  • Vasilakos J; Department of Molecular Genetics and Microbiology and Department of Immunology, Duke University, NC, USA.
  • Fox CB; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center Durham, NC, USA.
  • Reed SG; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, 954, Gatewood Road, Atlanta, GA, USA.
  • Haynes BF; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, 954, Gatewood Road, Atlanta, GA, USA.
  • Crotty S; New Iberia Research Center, University of Louisiana Lafayette, New Iberia, LA, USA.
  • Ahmed R; 3M Drug Delivery Systems, St. Paul, MN, USA.
  • Pulendran B; 3M Drug Delivery Systems, St. Paul, MN, USA.
Sci Immunol ; 5(48)2020 06 19.
Article en En | MEDLINE | ID: mdl-32561559

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Plasmáticas / Ácidos Esteáricos / Glicoproteínas de Membrana / Receptor Toll-Like 7 / Receptor Toll-Like 8 / Productos del Gen env del Virus de la Inmunodeficiencia Humana / Inmunidad Humoral / Compuestos Heterocíclicos con 3 Anillos / Macaca mulatta Límite: Animals Idioma: En Revista: Sci Immunol Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Plasmáticas / Ácidos Esteáricos / Glicoproteínas de Membrana / Receptor Toll-Like 7 / Receptor Toll-Like 8 / Productos del Gen env del Virus de la Inmunodeficiencia Humana / Inmunidad Humoral / Compuestos Heterocíclicos con 3 Anillos / Macaca mulatta Límite: Animals Idioma: En Revista: Sci Immunol Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos