Screen identifies DYRK1B network as mediator of transcription repression on damaged chromatin.

Dong, Chao; West, Kirk L; Tan, Xin Yi; Li, Junshi; Ishibashi, Toyotaka; Yu, Cheng-Han; Sy, Shirley M H; Leung, Justin W C; Huen, Michael S Y

Dong, Chao; West, Kirk L; Tan, Xin Yi; Li, Junshi; Ishibashi, Toyotaka; Yu, Cheng-Han; Sy, Shirley M H; Leung, Justin W C; Huen, Michael S Y.

Afiliación

Dong C; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
West KL; Department of Radiation Oncology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205.
Tan XY; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Li J; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Ishibashi T; Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, NT, Hong Kong SAR, China.
Yu CH; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Sy SMH; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Leung JWC; Department of Radiation Oncology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205; jwleung@uams.edu huen.michael@hku.hk.
Huen MSY; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China; jwleung@uams.edu huen.michael@hku.hk.

Proc Natl Acad Sci U S A ; 117(29): 17019-17030, 2020 07 21.

Article en En | MEDLINE | ID: mdl-32611815

Asunto(s)

Cromatina; Reparación del ADN/genética; Proteínas Serina-Treonina Quinasas; Proteínas Tirosina Quinasas; Transcripción Genética/genética; Línea Celular Tumoral; Cromatina/genética; Cromatina/metabolismo; Roturas del ADN de Doble Cadena; Silenciador del Gen; Antígenos de Histocompatibilidad/genética; Antígenos de Histocompatibilidad/metabolismo; N-Metiltransferasa de Histona-Lisina/genética; N-Metiltransferasa de Histona-Lisina/metabolismo; Humanos; Proteínas Serina-Treonina Quinasas/genética; Proteínas Serina-Treonina Quinasas/metabolismo; Proteínas Tirosina Quinasas/genética; Proteínas Tirosina Quinasas/metabolismo; Quinasas DyrK

Palabras clave

DNA damage; DNA double-strand breaks; DNA repair; DYRK1B; transcription

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transcripción Genética / Proteínas Tirosina Quinasas / Cromatina / Proteínas Serina-Treonina Quinasas / Reparación del ADN Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article País de afiliación: China

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google