Applications of Bacillus subtilis Spores in Biotechnology and Advanced Materials.
Appl Environ Microbiol
; 86(17)2020 08 18.
Article
en En
| MEDLINE
| ID: mdl-32631858
ABSTRACT
The bacterium Bacillus subtilis has long been an important subject for basic studies. However, this organism has also had industrial applications due to its easy genetic manipulation, favorable culturing characteristics for large-scale fermentation, superior capacity for protein secretion, and generally recognized as safe (GRAS) status. In addition, as the metabolically dormant form of B. subtilis, its spores have attracted great interest due to their extreme resistance to many environmental stresses, which makes spores a novel platform for a variety of applications. In this review, we summarize both conventional and emerging applications of B. subtilis spores, with a focus on how their unique characteristics have led to innovative applications in many areas of technology, including generation of stable and recyclable enzymes, synthetic biology, drug delivery, and material sciences. Ultimately, this review hopes to inspire the scientific community to leverage interdisciplinary approaches using spores to address global concerns about food shortages, environmental protection, and health care.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Esporas Bacterianas
/
Bacillus subtilis
/
Biotecnología
/
Materiales de Construcción
Idioma:
En
Revista:
Appl Environ Microbiol
Año:
2020
Tipo del documento:
Article
País de afiliación:
Estados Unidos