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The Phosphodiesterase-4 Inhibitor Roflumilast, a Potential Treatment for the Comorbidity of Memory Loss and Depression in Alzheimer's Disease: A Preclinical Study in APP/PS1 Transgenic Mice.
Wang, Hao; Zhang, Fang-Fang; Xu, Yong; Fu, Hua-Rong; Wang, Xiao-Dan; Wang, Lei; Chen, Wei; Xu, Xiao-Yan; Gao, Yong-Feng; Zhang, Ji-Guo; Zhang, Han-Ting.
Afiliación
  • Wang H; Institute of Pharmacology, Shandong First Medical University and Shandong Academy of Medical Sciences, Tai'an, China.
  • Zhang FF; Institute of Pharmacology, Shandong First Medical University and Shandong Academy of Medical Sciences, Tai'an, China.
  • Xu Y; Institute of Pharmacology, Shandong First Medical University and Shandong Academy of Medical Sciences, Tai'an, China.
  • Fu HR; Institute of Pharmacology, Shandong First Medical University and Shandong Academy of Medical Sciences, Tai'an, China.
  • Wang XD; Institute of Pharmacology, Shandong First Medical University and Shandong Academy of Medical Sciences, Tai'an, China.
  • Wang L; Institute of Pharmacology, Shandong First Medical University and Shandong Academy of Medical Sciences, Tai'an, China.
  • Chen W; Institute of Pharmacology, Shandong First Medical University and Shandong Academy of Medical Sciences, Tai'an, China.
  • Xu XY; Institute of Pharmacology, Shandong First Medical University and Shandong Academy of Medical Sciences, Tai'an, China.
  • Gao YF; Institute of Pharmacology, Shandong First Medical University and Shandong Academy of Medical Sciences, Tai'an, China.
  • Zhang JG; Institute of Pharmacology, Shandong First Medical University and Shandong Academy of Medical Sciences, Tai'an, China.
  • Zhang HT; Departments of Neuroscience and Behavioral Medicine & Psychiatry, the Rockefeller Neuroscience Institute, West Virginia University Health Sciences Center, Morgantown, West Virginia.
Int J Neuropsychopharmacol ; 23(10): 700-711, 2020 12 10.
Article en En | MEDLINE | ID: mdl-32645141
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Benzamidas / Corteza Cerebral / Depresión / Inhibidores de Fosfodiesterasa 4 / Enfermedad de Alzheimer / Aminopiridinas / Trastornos de la Memoria Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Int J Neuropsychopharmacol Asunto de la revista: NEUROLOGIA / PSICOFARMACOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Benzamidas / Corteza Cerebral / Depresión / Inhibidores de Fosfodiesterasa 4 / Enfermedad de Alzheimer / Aminopiridinas / Trastornos de la Memoria Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Int J Neuropsychopharmacol Asunto de la revista: NEUROLOGIA / PSICOFARMACOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: China