Loss of histone H3 trimethylation on lysine 27 and nuclear expression of transducin-like enhancer 1 in primary intracranial sarcoma, DICER1-mutant.

Alexandrescu, Sanda; Meredith, David M; Lidov, Hart G; Alaggio, Rita; Novello, Mariangela; Ligon, Keith L; Vargas, Sara O

Alexandrescu, Sanda; Meredith, David M; Lidov, Hart G; Alaggio, Rita; Novello, Mariangela; Ligon, Keith L; Vargas, Sara O.

Afiliación

Alexandrescu S; Department of Pathology, Boston Children's Hospital, Boston, MA, USA.
Meredith DM; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Lidov HG; Department of Pathology, Boston Children's Hospital, Boston, MA, USA.
Alaggio R; Department of Pathology, Bambino Gesu Hospital, Rome, Italy.
Novello M; Department of Pathology, San Bartolo Hospital, Vicenza, Italy.
Ligon KL; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Vargas SO; Department of Pathology, Boston Children's Hospital, Boston, MA, USA.

Histopathology ; 78(2): 265-275, 2021 Jan.

Article en En | MEDLINE | ID: mdl-32692439

Asunto(s)

Neoplasias Encefálicas; ARN Helicasas DEAD-box/genética; Histonas/metabolismo; Ribonucleasa III/genética; Sarcoma; Transducina; Adolescente; Anciano; Biomarcadores de Tumor/metabolismo; Neoplasias Encefálicas/genética; Neoplasias Encefálicas/patología; Niño; Femenino; Secuenciación de Nucleótidos de Alto Rendimiento; Humanos; Inmunohistoquímica/métodos; Lactante; Lisina/metabolismo; Masculino; Metilación; Mutación; Sarcoma/genética; Sarcoma/patología; Transducina/genética; Transducina/metabolismo

Palabras clave

DICER1; DICER1 syndrome; H3K27me3; TLE1; primary intracranial sarcoma

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sarcoma / Neoplasias Encefálicas / Histonas / Transducina / Ribonucleasa III / ARN Helicasas DEAD-box Límite: Adolescent / Aged / Child / Female / Humans / Infant / Male Idioma: En Revista: Histopathology Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

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