Detoxification of Ochratoxin A by a novel Aspergillus oryzae strain and optimization of its biodegradation.
Rev Argent Microbiol
; 53(1): 48-58, 2021.
Article
en En
| MEDLINE
| ID: mdl-32693928
ABSTRACT
The mycotoxin Ochratoxin A (OTA) causes serious health risks and is found in food products throughout the world. The most promising method to detoxify this compound is biodegradation. In this study, Aspergillus oryzae strain M30011 was isolated and characterized based on its considerable capacity to degrade OTA. The degradation product (compound I) of A. oryzae-treated OTA was isolated, and its toxicity response was also evaluated. Furthermore, the relationships between three key cultivation condition factors affecting the OTA degradation rate were examined using the response surface methodology (RSM). Compound I was identified as ochratoxin α (C11H9O5Cl), and the toxicity response experiments indicated that A. oryzae detoxified OTA to a great extent. A maximum degradation rate of 94% was observed after 72h. This study demonstrates the potential for using A. oryzae to detoxify OTA and suggests that it could be applied in the food industry to improve food safety and quality.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Aspergillus oryzae
/
Micotoxinas
/
Ocratoxinas
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Rev Argent Microbiol
Año:
2021
Tipo del documento:
Article