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Ciprofloxacin-Collagen-Based Materials with Potential Oral Surgical Applications.
Ioan, Daniel-Cristian; Rau, Ileana; Albu Kaya, Madalina Georgiana; Radu, Nicoleta; Bostan, Marinela; Zgârian, Roxana Gabriela; Tihan, Gratiela Teodora; Dinu-Pîrvu, Cristina-Elena; Lupuliasa, Alina; Ghica, Mihaela Violeta.
Afiliación
  • Ioan DC; Department of General Chemistry, Faculty of Applied Chemistry and Materials Science, University POLITEHNICA of Bucharest, 1-7 Gh. Polizu Str., 011061 Bucharest, Romania.
  • Rau I; Department of General Chemistry, Faculty of Applied Chemistry and Materials Science, University POLITEHNICA of Bucharest, 1-7 Gh. Polizu Str., 011061 Bucharest, Romania.
  • Albu Kaya MG; Department of Collagen, National Research and Development Institute for Textile and Leather (INCDTP), Division Leather and Footwear Research Institute, 93 Ion Minulescu Str., 031215 Bucharest, Romania.
  • Radu N; Faculty of Biotechnology, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 54 Marasti Boulevard, 011464 Bucharest, Romania.
  • Bostan M; Biotechnology Department, National Institute for Chemistry and Petrochemistry R&D of Bucharest, 202 Splaiul Independentei, 060021 Bucharest, Romania.
  • Zgârian RG; Institute of Virology Stefan S. Nicolau, Immunology Centre, 285 Mihai Bravu Avenue, 030304 Bucharest, Romania.
  • Tihan GT; Department of General Chemistry, Faculty of Applied Chemistry and Materials Science, University POLITEHNICA of Bucharest, 1-7 Gh. Polizu Str., 011061 Bucharest, Romania.
  • Dinu-Pîrvu CE; Department of General Chemistry, Faculty of Applied Chemistry and Materials Science, University POLITEHNICA of Bucharest, 1-7 Gh. Polizu Str., 011061 Bucharest, Romania.
  • Lupuliasa A; Department of Physical and Colloidal Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy "Carol Davila", 6 Traian Vuia Str., 020956 Bucharest, Romania.
  • Ghica MV; Department of Physical and Colloidal Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy "Carol Davila", 6 Traian Vuia Str., 020956 Bucharest, Romania.
Polymers (Basel) ; 12(9)2020 Aug 25.
Article en En | MEDLINE | ID: mdl-32854342
ABSTRACT
We report in this paper the synthesis and characterization of a new collagen-based material. This material was obtained in a spongy form and was functionalized with an antibiotic, ciprofloxacin. The targeted applications of these kind of materials concern the post-operative prophylaxis. The in vitro tests (antimicrobial, cytotoxic, drug release) showed that sponges with a concentration of 0.75 g of ciprofloxacin per gram of collagen could be beneficial for the desired applications.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Polymers (Basel) Año: 2020 Tipo del documento: Article País de afiliación: Rumanía
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Polymers (Basel) Año: 2020 Tipo del documento: Article País de afiliación: Rumanía