Clostridioides difficile Binary Toxin Is Recognized by the Toll-Like Receptor 2/6 Heterodimer to Induce a Nuclear Factor-&#954;B Response.

Simpson, Morgan; Frisbee, Alyse; Kumar, Pankaj; Schwan, Carsten; Aktories, Klaus; Petri, William A

Clostridioides difficile Binary Toxin Is Recognized by the Toll-Like Receptor 2/6 Heterodimer to Induce a Nuclear Factor-κB Response.

Simpson, Morgan; Frisbee, Alyse; Kumar, Pankaj; Schwan, Carsten; Aktories, Klaus; Petri, William A.

Afiliación

Simpson M; Department of Pathology, University of Virginia, Charlottesville, Virginia, USA.
Frisbee A; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia, USA.
Kumar P; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA.
Schwan C; Institute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Aktories K; Institute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Petri WA; Department of Pathology, University of Virginia, Charlottesville, Virginia, USA.

J Infect Dis ; 225(7): 1296-1300, 2022 04 01.

Article en En | MEDLINE | ID: mdl-33011801

Asunto(s)

Clostridioides difficile; Infecciones por Clostridium; Animales; Anticuerpos Antibacterianos; Ratones; FN-kappa B; Receptor Toll-Like 2/genética; Receptor Toll-Like 6

Palabras clave

Clostridioides difficile; CDT; NF-κB; TLR2; TLR6; binary toxin; immune response; innate immunity

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Clostridioides difficile / Infecciones por Clostridium Límite: Animals Idioma: En Revista: J Infect Dis Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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