A Systematic Evaluation of High-Throughput Sequencing Approaches to Identify Low-Frequency Single Nucleotide Variants in Viral Populations.

King, David J; Freimanis, Graham; Lasecka-Dykes, Lidia; Asfor, Amin; Ribeca, Paolo; Waters, Ryan; King, Donald P; Laing, Emma

King, David J; Freimanis, Graham; Lasecka-Dykes, Lidia; Asfor, Amin; Ribeca, Paolo; Waters, Ryan; King, Donald P; Laing, Emma.

Afiliación

King DJ; The Pirbright Institute, Woking, Surrey GU24 0NF, UK.
Freimanis G; Department of Microbial and Cellular Sciences, Faculty of Health and Medical Sciences, School of Biosciences and Medicine, University of Surrey, Guildford GU2 7XH, UK.
Lasecka-Dykes L; The Pirbright Institute, Woking, Surrey GU24 0NF, UK.
Asfor A; The Pirbright Institute, Woking, Surrey GU24 0NF, UK.
Ribeca P; The Pirbright Institute, Woking, Surrey GU24 0NF, UK.
Waters R; Department of Pathology and Infectious Diseases, Faculty of Health and Medical sciences, School of Veterinary Medicine, University of Surrey, Guilford GU2 7XH, UK.
King DP; Biomathematics and Statistics Scotland, Edinburgh, Midlothian EH9 3FD, UK.
Laing E; The Pirbright Institute, Woking, Surrey GU24 0NF, UK.

Viruses ; 12(10)2020 10 20.

Article en En | MEDLINE | ID: mdl-33092085

Asunto(s)

Secuenciación de Nucleótidos de Alto Rendimiento/métodos; Polimorfismo de Nucleótido Simple/genética; Virus/genética; ADN Viral; Genes Virales; Variación Genética; Genoma Viral; Técnicas In Vitro/métodos; Modelos Teóricos; ARN Viral

Palabras clave

high-throughput sequencing; sequencing error; sub-consensus variants; viral populations

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Virus / Polimorfismo de Nucleótido Simple / Secuenciación de Nucleótidos de Alto Rendimiento Tipo de estudio: Prognostic_studies Idioma: En Revista: Viruses Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido

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