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Longitudinal study of breast cancer risk markers.
Zarwan, Corrine; Diamond, Olivia; Lam, Prudence; Ghebremichael, Musie S; Lotz, Margaret; Shen, Abra H; Sharifi, Sheida; Rozhansky, Flora; Gore, Teresa Ann; Pories, Susan E.
Afiliación
  • Zarwan C; Lahey Hospital and Medical Center, Burlington, MA, USA.
  • Diamond O; Tufts School of Medicine, Boston, MA, USA.
  • Lam P; Mount Auburn Hospital, Cambridge, MA, USA.
  • Ghebremichael MS; Harvard Medical School, Boston, MA, USA.
  • Lotz M; Mount Auburn Hospital, Cambridge, MA, USA.
  • Shen AH; Harvard Medical School, Boston, MA, USA.
  • Sharifi S; Harvard School of Public Health and Ragon Institute, Cambridge, MA, USA.
  • Rozhansky F; Mount Auburn Hospital, Cambridge, MA, USA.
  • Gore TA; HMS IV, Harvard Medical School, Boston, MA, USA.
  • Pories SE; Lahey Hospital and Medical Center, Burlington, MA, USA.
Breast J ; 27(1): 48-51, 2021 01.
Article en En | MEDLINE | ID: mdl-33099843
ABSTRACT
Atypical hyperplasia (AH) and lobular carcinoma in situ (LCIS) are markers for an increased risk of breast cancer, yet outcomes for these diagnoses are not well-documented. In this study, all breast biopsies performed for radiologic abnormalities over a 10-year period were reviewed. Patients with AH or LCIS were followed for an additional 10 years to assess subsequent rates of cancer diagnosis. Long-term follow-up showed that 25 (7.8%) patients with AH and 5 patients with LCIS (5.7%) developed breast cancer over the follow-up period, a lower rate of breast cancer development than predicted by risk models.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Carcinoma in Situ / Carcinoma Lobular / Carcinoma de Mama in situ Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Breast J Asunto de la revista: NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Carcinoma in Situ / Carcinoma Lobular / Carcinoma de Mama in situ Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Breast J Asunto de la revista: NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos