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A cross-industry collaboration to assess if acute oral toxicity (Q)SAR models are fit-for-purpose for GHS classification and labelling.
Bercu, Joel; Masuda-Herrera, Melisa J; Trejo-Martin, Alejandra; Hasselgren, Catrin; Lord, Jean; Graham, Jessica; Schmitz, Matthew; Milchak, Lawrence; Owens, Colin; Lal, Surya Hari; Robinson, Richard Marchese; Whalley, Sarah; Bellion, Phillip; Vuorinen, Anna; Gromek, Kamila; Hawkins, William A; van de Gevel, Iris; Vriens, Kathleen; Kemper, Raymond; Naven, Russell; Ferrer, Pierre; Myatt, Glenn J.
Afiliación
  • Bercu J; Gilead Sciences, 333 Lakeside Drive, Foster City, CA, USA.
  • Masuda-Herrera MJ; Gilead Sciences, 333 Lakeside Drive, Foster City, CA, USA.
  • Trejo-Martin A; Gilead Sciences, 333 Lakeside Drive, Foster City, CA, USA.
  • Hasselgren C; Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080, USA.
  • Lord J; Ultragenyx, 60 Leveroni Court, Novato, CA, 94949, USA.
  • Graham J; Bristol Myers Squibb, 1 Squibb Dr, New Brunswick, NJ, 08903, USA.
  • Schmitz M; AbbVie Inc., North Chicago, IL, USA.
  • Milchak L; 3M Company, 3M Center, St. Paul, MN, 55144-1000, USA.
  • Owens C; 3M Company, 3M Center, St. Paul, MN, 55144-1000, USA.
  • Lal SH; Syngenta Crop Protection, Product Safety Department, Jealott's Hill International Research Centre, Bracknell, Berkshire, RG42 6EY, UK(1).
  • Robinson RM; Syngenta Crop Protection, Product Safety Department, Jealott's Hill International Research Centre, Bracknell, Berkshire, RG42 6EY, UK(1).
  • Whalley S; Syngenta Crop Protection, Product Safety Department, Jealott's Hill International Research Centre, Bracknell, Berkshire, RG42 6EY, UK(1).
  • Bellion P; DSM Nutritional Products, Kaiseraugst, Switzerland.
  • Vuorinen A; DSM Nutritional Products, Kaiseraugst, Switzerland.
  • Gromek K; Galapagos SASU, 102 Avenue Gaston Roussel, 93230, Romainville, France.
  • Hawkins WA; GlaxoSmithKline, Park Road, Ware, Hertfordshire, SG12 0DP, United Kingdom.
  • van de Gevel I; Janssen Pharmaceutical Companies of Johnson & Johnson, 2340, Beerse, Belgium.
  • Vriens K; Janssen Pharmaceutical Companies of Johnson & Johnson, 2340, Beerse, Belgium.
  • Kemper R; Vertex Pharmaceuticals Inc., Discovery and Investigative Toxicology, 50 Northern Ave, Boston, MA, USA.
  • Naven R; Vertex Pharmaceuticals Inc., Discovery and Investigative Toxicology, 50 Northern Ave, Boston, MA, USA.
  • Ferrer P; Department of Veterinary Physiology and Pharmacology, Interdisciplinary Faculty of Toxicology Program, Texas A&M University, 4466 TAMU, College Station, TX, 77843-4466, USA.
  • Myatt GJ; Leadscope (an Instem company), 1393 Dublin Rd, Columbus, OH, 43215, USA. Electronic address: gmyatt@leadscope.com.
Regul Toxicol Pharmacol ; 120: 104843, 2021 Mar.
Article en En | MEDLINE | ID: mdl-33340644

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Etiquetado de Productos / Simulación por Computador / Colaboración Intersectorial / Relación Estructura-Actividad Cuantitativa / Citotoxinas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Regul Toxicol Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Etiquetado de Productos / Simulación por Computador / Colaboración Intersectorial / Relación Estructura-Actividad Cuantitativa / Citotoxinas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Regul Toxicol Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos