Monocyte CD169 expression in COVID-19 patients upon intensive care unit admission.
Cytometry A
; 99(5): 466-471, 2021 05.
Article
en En
| MEDLINE
| ID: mdl-33547747
ABSTRACT
During the second surge of COVID-19 in France (fall 2020), we assessed the expression of monocyte CD169 (i.e., Siglec-1, one of the numerous IFN-stimulated genes) upon admission to intensive care units of 45 patients with RT-PCR-confirmed SARS-CoV2 pulmonary infection. Overall, CD169 expression was strongly induced on circulating monocytes of COVID-19 patients compared with healthy donors and patients with bacterial sepsis. Beyond its contribution at the emergency department, CD169 testing may be also helpful for patients' triage at the ICU to rapidly reinforce suspicion of COVID-19 etiology in patients with acute respiratory failure awaiting for PCR results for definitive diagnosis.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Admisión del Paciente
/
Monocitos
/
Lectina 1 Similar a Ig de Unión al Ácido Siálico
/
SARS-CoV-2
/
COVID-19
/
Unidades de Cuidados Intensivos
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Cytometry A
Año:
2021
Tipo del documento:
Article
País de afiliación:
Francia