[Changes in the immune status of patients with chronic stasis of the large intestine]. / Izmeneniia v immunnom statuse bol'nykh khronicheskim stazom tolstoi kishki.

ABSTRACT

The authors analyzed immunological changes in 56 patients with chronic colon stasis at the compensated and decompensated stages. Clinicoimmunological investigation of these patients permitted the detection of considerable changes in the system of homeostasis against a background of chronic inflammation of the colon mucous membrane, dysbacteriosis, colon microflora, and intoxication. Signs of secondary immunodeficiency with simultaneous involvement of compensatory mechanisms of nonspecific and specific body defence were noted in the patients. More profound changes were revealed at the decompensated stage. Immunomodulating measures produce a normalizing effect on immunity indices and on the entire system of homeostasis.