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HSP25 Vaccination Attenuates Atherogenesis via Upregulation of LDLR Expression, Lowering of PCSK9 Levels and Curbing of Inflammation.
Chen, Yong-Xiang; Shi, Chunhua; Deng, Jingti; Diao, Catherine; Maarouf, Nadia; Rosin, Matthew; Shrivastava, Vipul; Hu, Angie A; Bharadwa, Sonya; Adijiang, Ayinuer; Ulke-Lemee, Annegret; Gwilym, Brenig; Hellmich, Alexandria; Malozzi, Christopher; Batulan, Zarah; Dean, Jonathan L E; Ramirez, F Daniel; Liu, Jingwen; Gerthoffer, William T; O'Brien, Edward R.
Afiliación
  • Chen YX; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary Cumming School of Medicine, Alberta, Canada (Y.-X.C., C.S., J.D., C.D., N.M., M.R., V.S., A.A.H., S.B., A.A., A.U.-L., B.G., Z.B., E.R.O.).
  • Shi C; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary Cumming School of Medicine, Alberta, Canada (Y.-X.C., C.S., J.D., C.D., N.M., M.R., V.S., A.A.H., S.B., A.A., A.U.-L., B.G., Z.B., E.R.O.).
  • Deng J; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary Cumming School of Medicine, Alberta, Canada (Y.-X.C., C.S., J.D., C.D., N.M., M.R., V.S., A.A.H., S.B., A.A., A.U.-L., B.G., Z.B., E.R.O.).
  • Diao C; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary Cumming School of Medicine, Alberta, Canada (Y.-X.C., C.S., J.D., C.D., N.M., M.R., V.S., A.A.H., S.B., A.A., A.U.-L., B.G., Z.B., E.R.O.).
  • Maarouf N; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary Cumming School of Medicine, Alberta, Canada (Y.-X.C., C.S., J.D., C.D., N.M., M.R., V.S., A.A.H., S.B., A.A., A.U.-L., B.G., Z.B., E.R.O.).
  • Rosin M; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary Cumming School of Medicine, Alberta, Canada (Y.-X.C., C.S., J.D., C.D., N.M., M.R., V.S., A.A.H., S.B., A.A., A.U.-L., B.G., Z.B., E.R.O.).
  • Shrivastava V; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary Cumming School of Medicine, Alberta, Canada (Y.-X.C., C.S., J.D., C.D., N.M., M.R., V.S., A.A.H., S.B., A.A., A.U.-L., B.G., Z.B., E.R.O.).
  • Hu AA; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary Cumming School of Medicine, Alberta, Canada (Y.-X.C., C.S., J.D., C.D., N.M., M.R., V.S., A.A.H., S.B., A.A., A.U.-L., B.G., Z.B., E.R.O.).
  • Bharadwa S; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary Cumming School of Medicine, Alberta, Canada (Y.-X.C., C.S., J.D., C.D., N.M., M.R., V.S., A.A.H., S.B., A.A., A.U.-L., B.G., Z.B., E.R.O.).
  • Adijiang A; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary Cumming School of Medicine, Alberta, Canada (Y.-X.C., C.S., J.D., C.D., N.M., M.R., V.S., A.A.H., S.B., A.A., A.U.-L., B.G., Z.B., E.R.O.).
  • Ulke-Lemee A; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary Cumming School of Medicine, Alberta, Canada (Y.-X.C., C.S., J.D., C.D., N.M., M.R., V.S., A.A.H., S.B., A.A., A.U.-L., B.G., Z.B., E.R.O.).
  • Gwilym B; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary Cumming School of Medicine, Alberta, Canada (Y.-X.C., C.S., J.D., C.D., N.M., M.R., V.S., A.A.H., S.B., A.A., A.U.-L., B.G., Z.B., E.R.O.).
  • Hellmich A; Department of Biochemistry and Molecular Biology, University of South Alabama College of Medicine, Mobile (A.H., W.T.G.).
  • Malozzi C; Department of Internal Medicine, University of South Alabama Medical Center, Mobile (C.M.).
  • Batulan Z; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary Cumming School of Medicine, Alberta, Canada (Y.-X.C., C.S., J.D., C.D., N.M., M.R., V.S., A.A.H., S.B., A.A., A.U.-L., B.G., Z.B., E.R.O.).
  • Dean JLE; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, United Kingdom (J.L.E.D.).
  • Ramirez FD; Division of Cardiology, University of Ottawa Heart Institute, Ontario, Canada (F.D.R.).
  • Liu J; Department of Veterans Affairs Palo Alto Health Care System, California (J.L.).
  • Gerthoffer WT; Department of Biochemistry and Molecular Biology, University of South Alabama College of Medicine, Mobile (A.H., W.T.G.).
  • O'Brien ER; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary Cumming School of Medicine, Alberta, Canada (Y.-X.C., C.S., J.D., C.D., N.M., M.R., V.S., A.A.H., S.B., A.A., A.U.-L., B.G., Z.B., E.R.O.).
Arterioscler Thromb Vasc Biol ; 41(6): e338-e353, 2021 06.
Article en En | MEDLINE | ID: mdl-33792343
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Aorta / Enfermedades de la Aorta / Receptores de LDL / Vacunas Sintéticas / Colesterol / Chaperonas Moleculares / Aterosclerosis / Proproteína Convertasa 9 / Proteínas de Choque Térmico Tipo de estudio: Observational_studies Límite: Aged80 Idioma: En Revista: Arterioscler Thromb Vasc Biol Asunto de la revista: ANGIOLOGIA Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Aorta / Enfermedades de la Aorta / Receptores de LDL / Vacunas Sintéticas / Colesterol / Chaperonas Moleculares / Aterosclerosis / Proproteína Convertasa 9 / Proteínas de Choque Térmico Tipo de estudio: Observational_studies Límite: Aged80 Idioma: En Revista: Arterioscler Thromb Vasc Biol Asunto de la revista: ANGIOLOGIA Año: 2021 Tipo del documento: Article