[Early Clinical Diagnosis of Anti-NMDA Receptor Encephalitis: Case Series and Literature Review]. / Diagnóstico clínico temprano de la Encefalitis Anti-Receptor NMDA: Serie de casos y revisión bibliográfica.
Vertex
; XXX(147): 1-8, 2020 Jan.
Article
en Es
| MEDLINE
| ID: mdl-33890921
ABSTRACT
Autoimmune encephalitis refers to a group of pathologies described in the last two decades, characterized by neuropsychiatric symptoms of subacute presentation, mediated by antibodies directed against neuronal membrane proteins. Within this group, encephalitis mediated by antibodies against the NMDA receptor of glutamate is a particular clinical entity, given that its expression is dominated by psychiatric symptoms that usually occur at the onset of the disease. In this paper we describe five cases of NMDA encephalitis in adult patients followed up in the last four years in a public hospital in the City of Buenos Aires, Argentina. We also include a review of the current literature. We emphasize the clinical description of the psychiatric symptoms of presentation, since these lead to the patient's first contact with the health system. Given the difficulty in our environment to implement the determination of autoantibodies, the ability to clinically recognize this pathology becomes paramount to establish an early preliminary diagnosis and not to delay immunosuppressive therapy, thus allowing for a better prognosis.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Encefalitis Antirreceptor N-Metil-D-Aspartato
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Adult
/
Humans
País/Región como asunto:
America do sul
/
Argentina
Idioma:
Es
Revista:
Vertex
Asunto de la revista:
PSIQUIATRIA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Argentina