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Design, synthesis and biological evaluation of selective histone deacetylase 6 (HDAC6) inhibitors bearing benzoindazole or pyrazoloindazole scaffold as surface recognition motif.
Xu, Qihao; Mou, Yanhua; Wang, Siyuan; Gao, Xiaoxiao; Zhang, Yulong; Wang, Zhi; Xu, Xiangwei; Han, Yu; Jia, Wenlong; Zhang, Meihui; Zhao, Linxiang; Liu, Dan.
Afiliación
  • Xu Q; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Mou Y; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Wang S; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Gao X; Department of Pharmacology, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Zhang Y; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Wang Z; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Xu X; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Han Y; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Jia W; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Zhang M; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Zhao L; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: linxiang.zhao@vip.sina.com.
  • Liu D; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: sammyld@163.com.
Bioorg Chem ; 111: 104910, 2021 06.
Article en En | MEDLINE | ID: mdl-33894432
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diseño de Fármacos / Inhibidores de Histona Desacetilasas / Histona Desacetilasa 6 / Indazoles Límite: Animals / Humans Idioma: En Revista: Bioorg Chem Año: 2021 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Diseño de Fármacos / Inhibidores de Histona Desacetilasas / Histona Desacetilasa 6 / Indazoles Límite: Animals / Humans Idioma: En Revista: Bioorg Chem Año: 2021 Tipo del documento: Article País de afiliación: China