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Self-driving armored CAR-T cells overcome a suppressive milieu and eradicate CD19+ Raji lymphoma in preclinical models.
Webster, Brian; Xiong, Ying; Hu, Peirong; Wu, Darong; Alabanza, Leah; Orentas, Rimas J; Dropulic, Boro; Schneider, Dina.
Afiliación
  • Webster B; Translational Research and Development, Lentigen, a Miltenyi Biotec Company, 1201 Clopper Road, Gaithersburg, MD 20878, USA; Research and Development, Miltenyi Biotec, Friedrich-Ebert-Strasse 68, 51429 Bergisch Gladbach, Germany. Electronic address: brianwe@miltenyibiotec.de.
  • Xiong Y; Translational Research and Development, Lentigen, a Miltenyi Biotec Company, 1201 Clopper Road, Gaithersburg, MD 20878, USA.
  • Hu P; Translational Research and Development, Lentigen, a Miltenyi Biotec Company, 1201 Clopper Road, Gaithersburg, MD 20878, USA.
  • Wu D; Translational Research and Development, Lentigen, a Miltenyi Biotec Company, 1201 Clopper Road, Gaithersburg, MD 20878, USA.
  • Alabanza L; Translational Research and Development, Lentigen, a Miltenyi Biotec Company, 1201 Clopper Road, Gaithersburg, MD 20878, USA.
  • Orentas RJ; Translational Research and Development, Lentigen, a Miltenyi Biotec Company, 1201 Clopper Road, Gaithersburg, MD 20878, USA; Seattle Children's Research Institute and Department of Pediatrics, University of Washington School of Medicine, 4800 Sand Point Way, N.E., Seattle, WA 98105, USA.
  • Dropulic B; Translational Research and Development, Lentigen, a Miltenyi Biotec Company, 1201 Clopper Road, Gaithersburg, MD 20878, USA. Electronic address: boro.dropulic@miltenyi.com.
  • Schneider D; Translational Research and Development, Lentigen, a Miltenyi Biotec Company, 1201 Clopper Road, Gaithersburg, MD 20878, USA. Electronic address: dina.schneider@miltenyi.com.
Mol Ther ; 29(9): 2691-2706, 2021 09 01.
Article en En | MEDLINE | ID: mdl-33974997
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de Antígenos de Linfocitos T / Inmunoterapia Adoptiva / FN-kappa B / Linfoma de Burkitt / Factor de Transcripción AP-1 / Factor de Transcripción STAT5 / Receptor Tipo II de Factor de Crecimiento Transformador beta Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Mol Ther Asunto de la revista: BIOLOGIA MOLECULAR / TERAPEUTICA Año: 2021 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de Antígenos de Linfocitos T / Inmunoterapia Adoptiva / FN-kappa B / Linfoma de Burkitt / Factor de Transcripción AP-1 / Factor de Transcripción STAT5 / Receptor Tipo II de Factor de Crecimiento Transformador beta Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Mol Ther Asunto de la revista: BIOLOGIA MOLECULAR / TERAPEUTICA Año: 2021 Tipo del documento: Article