Overexpression of transcription factor BLIMP1/prdm1 leads to growth inhibition and enhanced secretory capacity in Chinese hamster ovary cells.

Torres, Mauro; Dickson, Alan J

Torres, Mauro; Dickson, Alan J.

Afiliación

Torres M; Manchester Institute of Biotechnology, Faculty of Science and Engineering, University of Manchester, Manchester, UK; Department of Chemical Engineering and Analytical Science, Biochemical and Bioprocess Engineering Group, University of Manchester, Manchester, UK.
Dickson AJ; Manchester Institute of Biotechnology, Faculty of Science and Engineering, University of Manchester, Manchester, UK; Department of Chemical Engineering and Analytical Science, Biochemical and Bioprocess Engineering Group, University of Manchester, Manchester, UK. Electronic address: alan.dickson@manchester.ac.uk.

Metab Eng ; 67: 237-249, 2021 09.

Article en En | MEDLINE | ID: mdl-34265400

Asunto(s)

Regulación de la Expresión Génica; Factores de Transcripción; Animales; Células CHO; Cricetinae; Cricetulus; Proteínas Recombinantes/genética; Proteínas Recombinantes/metabolismo

Palabras clave

Biopharmaceuticals; CHO cells; Cell engineering; Growth inhibition; Metabolomics; prdm1/BLIMP1

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Regulación de la Expresión Génica Límite: Animals Idioma: En Revista: Metab Eng Asunto de la revista: ENGENHARIA BIOMEDICA / METABOLISMO Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido

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