Evidence-based management of preimplantation chromosomal mosaicism: lessons from the clinic.
Fertil Steril
; 116(5): 1220-1224, 2021 11.
Article
en En
| MEDLINE
| ID: mdl-34373104
ABSTRACT
Mosaic results obtained through preimplantation genetic testing for aneuploidy pose ongoing challenges to clinical practice. Thorough genetic counseling for patients considering mosaic embryo transfer is consistently recommended by many best-practice statements, and providers are charged with the task of assessing and explaining potential prenatal, neonatal, and long-term risks. However, an increasing amount of outcome data from transferred embryos with mosaic results do not show any evidence of increased risk to ongoing pregnancies or newborns. This article examines how to reconcile these data with the current practices for patient education about preimplantation genetic testing for aneuploidy and mosaic embryo risk assessment, through an evidence-based lens.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Diagnóstico Prenatal
/
Blastocisto
/
Pruebas Genéticas
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Técnicas Reproductivas Asistidas
/
Infertilidad
/
Mosaicismo
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Guideline
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Female
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Humans
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Male
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Pregnancy
Idioma:
En
Revista:
Fertil Steril
Año:
2021
Tipo del documento:
Article