Bioadhesive hydrogel comprising bilirubin/ß-cyclodextrin inclusion complexes promote diabetic wound healing.

Yao, Qing; Shi, Yannan; Xia, Xing; Tang, Yingying; Jiang, Xue; Zheng, Ya-Wen; Zhang, Hailin; Chen, Ruijie; Kou, Longfa

Yao, Qing; Shi, Yannan; Xia, Xing; Tang, Yingying; Jiang, Xue; Zheng, Ya-Wen; Zhang, Hailin; Chen, Ruijie; Kou, Longfa.

Afiliación

Yao Q; Department of Pharmacy, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Shi Y; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Xia X; Department of Pharmacy, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Tang Y; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Jiang X; Department of Pharmacy, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Zheng YW; Department of Pharmacy, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Zhang H; Central Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Chen R; Central Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Kou L; Department of Pharmacy, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

Pharm Biol ; 59(1): 1139-1149, 2021 Dec.

Article en En | MEDLINE | ID: mdl-34425063

Asunto(s)

Bilirrubina/farmacología; Diabetes Mellitus Experimental/tratamiento farmacológico; Cicatrización de Heridas/efectos de los fármacos; beta-Ciclodextrinas/química; Adhesivos; Animales; Antioxidantes/administración & dosificación; Antioxidantes/química; Antioxidantes/farmacología; Bilirrubina/administración & dosificación; Bilirrubina/química; Colágeno/metabolismo; Diabetes Mellitus Experimental/complicaciones; Células Endoteliales de la Vena Umbilical Humana; Humanos; Hidrogeles; Ratas; Solubilidad; Factores de Tiempo; Heridas y Lesiones/tratamiento farmacológico; Heridas y Lesiones/etiología

Palabras clave

Thiolated polyglutamic acid; anti-inflammation; bilirubin inclusion complex; macrophage polarization; rheological characterization; tissue remodelling

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cicatrización de Heridas / Bilirrubina / Beta-Ciclodextrinas / Diabetes Mellitus Experimental Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Pharm Biol Año: 2021 Tipo del documento: Article País de afiliación: China

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