TRIB3 regulates FSHR expression in human granulosa cells under high levels of free fatty acids.

Wang, Nan; Si, Chenchen; Xia, Lan; Wu, Xian; Zhao, Sheng; Xu, Huihui; Ding, Zhide; Niu, Zhihong

Wang, Nan; Si, Chenchen; Xia, Lan; Wu, Xian; Zhao, Sheng; Xu, Huihui; Ding, Zhide; Niu, Zhihong.

Afiliación

Wang N; Department of Gynecology and Obstetrics, Ruijin Hospital Affiliated with the Medical School of Shanghai Jiao Tong University, Shanghai, 200025, China.
Si C; Department of Gynecology and Obstetrics, Ruijin Hospital Affiliated with the Medical School of Shanghai Jiao Tong University, Shanghai, 200025, China.
Xia L; Department of Gynecology and Obstetrics, Ruijin Hospital Affiliated with the Medical School of Shanghai Jiao Tong University, Shanghai, 200025, China.
Wu X; Department of Gynecology and Obstetrics, Ruijin Hospital Affiliated with the Medical School of Shanghai Jiao Tong University, Shanghai, 200025, China.
Zhao S; Department of Gynecology and Obstetrics, Ruijin Hospital Affiliated with the Medical School of Shanghai Jiao Tong University, Shanghai, 200025, China.
Xu H; Department of Gynecology and Obstetrics, Ruijin Hospital Affiliated with the Medical School of Shanghai Jiao Tong University, Shanghai, 200025, China.
Ding Z; Department of Histology, Embryology, Genetics and Developmental Biology, Shanghai Key Laboratory for Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. zding@shsmu.edu.cn.
Niu Z; Department of Gynecology and Obstetrics, Ruijin Hospital Affiliated with the Medical School of Shanghai Jiao Tong University, Shanghai, 200025, China. kangniu@sina.com.

Reprod Biol Endocrinol ; 19(1): 139, 2021 Sep 09.

Article en En | MEDLINE | ID: mdl-34503515

Asunto(s)

Proteínas de Ciclo Celular/genética; Ácidos Grasos no Esterificados/metabolismo; Regulación de la Expresión Génica; Células de la Granulosa/metabolismo; Proteínas Serina-Treonina Quinasas/antagonistas & inhibidores; Receptores de HFE/genética; Proteínas Represoras/genética; Factor de Transcripción Activador 4/genética; Factor de Transcripción Activador 4/metabolismo; Adulto; Proteínas de Ciclo Celular/metabolismo; Línea Celular Tumoral; Células Cultivadas; Estradiol/metabolismo; Femenino; Fertilización In Vitro/métodos; Glucógeno Sintasa Quinasa 3 beta/genética; Glucógeno Sintasa Quinasa 3 beta/metabolismo; Humanos; Infertilidad Femenina/genética; Infertilidad Femenina/metabolismo; Infertilidad Femenina/terapia; Proteínas Serina-Treonina Quinasas/genética; Proteínas Serina-Treonina Quinasas/metabolismo; Proteínas Proto-Oncogénicas c-akt/genética; Proteínas Proto-Oncogénicas c-akt/metabolismo; Interferencia de ARN; Receptores de HFE/metabolismo; Proteínas Represoras/metabolismo; Transducción de Señal/genética

Palabras clave

Akt/GSK3ß pathway; Follicle stimulating hormone receptor (FSHR); Human granulosa cells; Palmitic acid; Tribbles pseudokinase 3 (TRIB3)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Represoras / Receptores de HFE / Regulación de la Expresión Génica / Proteínas Serina-Treonina Quinasas / Proteínas de Ciclo Celular / Ácidos Grasos no Esterificados / Células de la Granulosa Límite: Adult / Female / Humans Idioma: En Revista: Reprod Biol Endocrinol Asunto de la revista: ENDOCRINOLOGIA / MEDICINA REPRODUTIVA Año: 2021 Tipo del documento: Article País de afiliación: China

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