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Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer.
Chen, Ming; Chen, Runzhe; Jin, Ying; Li, Jun; Hu, Xin; Zhang, Jiexin; Fujimoto, Junya; Hubert, Shawna M; Gay, Carl M; Zhu, Bo; Tian, Yanhua; McGranahan, Nicholas; Lee, Won-Chul; George, Julie; Hu, Xiao; Chen, Yamei; Wu, Meijuan; Behrens, Carmen; Chow, Chi-Wan; Pham, Hoa H N; Fukuoka, Junya; Wu, Jia; Parra, Edwin Roger; Little, Latasha D; Gumbs, Curtis; Song, Xingzhi; Wu, Chang-Jiun; Diao, Lixia; Wang, Qi; Cardnell, Robert; Zhang, Jianhua; Wang, Jing; Le, Xiuning; Gibbons, Don L; Heymach, John V; Jack Lee, J; William, William N; Cheng, Chao; Glisson, Bonnie; Wistuba, Ignacio; Andrew Futreal, P; Thomas, Roman K; Reuben, Alexandre; Byers, Lauren A; Zhang, Jianjun.
Afiliación
  • Chen M; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, Guangdong, 510060, China. chenming@sysucc.org.cn.
  • Chen R; The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, Zhejiang, 310022, China. chenming@sysucc.org.cn.
  • Jin Y; Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, 310022, China. chenming@sysucc.org.cn.
  • Li J; Zhejiang Key Laboratory of Radiation Oncology, Hangzhou, Zhejiang, 310022, China. chenming@sysucc.org.cn.
  • Hu X; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, Guangdong, 510060, China.
  • Zhang J; Department of Thoracic/Head and Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Fujimoto J; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Hubert SM; The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, Zhejiang, 310022, China.
  • Gay CM; Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, 310022, China.
  • Zhu B; Zhejiang Key Laboratory of Radiation Oncology, Hangzhou, Zhejiang, 310022, China.
  • Tian Y; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • McGranahan N; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Lee WC; Department of Bioinformatics and Computational Biology, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • George J; Department of Translational Molecular Pathology, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Hu X; Department of Thoracic/Head and Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Chen Y; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Wu M; Department of Thoracic/Head and Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Behrens C; Department of Thoracic/Head and Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Chow CW; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Pham HHN; Department of Thoracic/Head and Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Fukuoka J; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Wu J; Cancer Research United Kingdom-University College London Lung Cancer Centre of Excellence, London, WC1E6BT, UK.
  • Parra ER; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Little LD; Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, 50931, Germany.
  • Gumbs C; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Cologne, 50937, Cologne, Germany.
  • Song X; The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, Zhejiang, 310022, China.
  • Wu CJ; Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, 310022, China.
  • Diao L; Zhejiang Key Laboratory of Radiation Oncology, Hangzhou, Zhejiang, 310022, China.
  • Wang Q; The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, Zhejiang, 310022, China.
  • Cardnell R; Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, 310022, China.
  • Zhang J; Zhejiang Key Laboratory of Radiation Oncology, Hangzhou, Zhejiang, 310022, China.
  • Wang J; The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, Zhejiang, 310022, China.
  • Le X; Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, 310022, China.
  • Gibbons DL; Zhejiang Key Laboratory of Radiation Oncology, Hangzhou, Zhejiang, 310022, China.
  • Heymach JV; Department of Thoracic/Head and Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Jack Lee J; Department of Translational Molecular Pathology, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • William WN; Department of Pathology, Nagasaki University Graduate school of Biomedical Sciences, Nagasaki, Japan.
  • Cheng C; Department of Pathology, Nagasaki University Graduate school of Biomedical Sciences, Nagasaki, Japan.
  • Glisson B; Department of Image Physics, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Wistuba I; Department of Translational Molecular Pathology, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Andrew Futreal P; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Thomas RK; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Reuben A; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Byers LA; Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
  • Zhang J; Department of Bioinformatics and Computational Biology, the University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, USA.
Nat Commun ; 12(1): 6655, 2021 11 17.
Article en En | MEDLINE | ID: mdl-34789716
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T / Carcinoma Pulmonar de Células Pequeñas / Neoplasias Pulmonares Tipo de estudio: Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T / Carcinoma Pulmonar de Células Pequeñas / Neoplasias Pulmonares Tipo de estudio: Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: China