Sweeteners Maintain Epithelial Barrier Function Through the miR-15b/RECK/MMP-9 Axis, Remodel Microbial Homeostasis, and Attenuate Dextran Sodium Sulfate-Induced Colitis in Mice.

Zhang, Xuejiao; Gu, Jiaxin; Zhao, Congying; Hu, Yaozhong; Zhang, Bowei; Wang, Jin; Lv, Huan; Ji, Xuemeng; Wang, Shuo

Zhang, Xuejiao; Gu, Jiaxin; Zhao, Congying; Hu, Yaozhong; Zhang, Bowei; Wang, Jin; Lv, Huan; Ji, Xuemeng; Wang, Shuo.

Afiliación

Zhang X; School of Medicine, Nankai University, Tianjin 300071, China.
Gu J; College of Food Science and Technology, Hebei Agricultural University, Baoding 071000, China.
Zhao C; School of Medicine, Nankai University, Tianjin 300071, China.
Hu Y; School of Medicine, Nankai University, Tianjin 300071, China.
Zhang B; School of Medicine, Nankai University, Tianjin 300071, China.
Wang J; School of Medicine, Nankai University, Tianjin 300071, China.
Lv H; School of Medicine, Nankai University, Tianjin 300071, China.
Ji X; School of Medicine, Nankai University, Tianjin 300071, China.
Wang S; School of Medicine, Nankai University, Tianjin 300071, China.

J Agric Food Chem ; 70(1): 171-183, 2022 Jan 12.

Article en En | MEDLINE | ID: mdl-34962394

Asunto(s)

Colitis; MicroARNs; Animales; Colitis/inducido químicamente; Colitis/tratamiento farmacológico; Colitis/genética; Colon; Sulfato de Dextran/efectos adversos; Modelos Animales de Enfermedad; Homeostasis; Metaloproteinasa 9 de la Matriz; Ratones; Ratones Endogámicos C57BL; MicroARNs/genética; Sulfatos; Edulcorantes

Palabras clave

MMP-9; gut microbiota; intestinal barrier; miRNA; non-nutritive sweeteners

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Colitis / MicroARNs Límite: Animals Idioma: En Revista: J Agric Food Chem Año: 2022 Tipo del documento: Article País de afiliación: China

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