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Design and synthesis of benzodiazepines as brain penetrating PARP-1 inhibitors.
Yu, Jiang; Gou, Wenfeng; Shang, Haihua; Cui, Yating; Sun, Xiao; Luo, Lingling; Hou, Wenbin; Sun, Tiemin; Li, Yiliang.
Afiliación
  • Yu J; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, Tianjin, China.
  • Gou W; Key Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, Ministry of Education, Shenyang, China.
  • Shang H; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, Tianjin, China.
  • Cui Y; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, Tianjin, China.
  • Sun X; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, Tianjin, China.
  • Luo L; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, Tianjin, China.
  • Hou W; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, Tianjin, China.
  • Sun T; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, Tianjin, China.
  • Li Y; Key Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, Ministry of Education, Shenyang, China.
J Enzyme Inhib Med Chem ; 37(1): 952-972, 2022 Dec.
Article en En | MEDLINE | ID: mdl-35317687
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Benzodiazepinas / Diseño de Fármacos / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Poli(ADP-Ribosa) Polimerasa-1 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Enzyme Inhib Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Benzodiazepinas / Diseño de Fármacos / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Poli(ADP-Ribosa) Polimerasa-1 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Enzyme Inhib Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: China