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The L467F-F508del Complex Allele Hampers Pharmacological Rescue of Mutant CFTR by Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Patients: The Value of the Ex Vivo Nasal Epithelial Model to Address Non-Responders to CFTR-Modulating Drugs.
Sondo, Elvira; Cresta, Federico; Pastorino, Cristina; Tomati, Valeria; Capurro, Valeria; Pesce, Emanuela; Lena, Mariateresa; Iacomino, Michele; Baffico, Ave Maria; Coviello, Domenico; Bandiera, Tiziano; Zara, Federico; Galietta, Luis J V; Bocciardi, Renata; Castellani, Carlo; Pedemonte, Nicoletta.
Afiliación
  • Sondo E; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.
  • Cresta F; UOSD Centro Fibrosi Cistica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.
  • Pastorino C; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, 16132 Genova, Italy.
  • Tomati V; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.
  • Capurro V; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.
  • Pesce E; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.
  • Lena M; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.
  • Iacomino M; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.
  • Baffico AM; UOC Laboratorio di Genetica Umana, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.
  • Coviello D; UOC Laboratorio di Genetica Umana, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.
  • Bandiera T; D3-PharmaChemistry, Fondazione Istituto Italiano di Tecnologia, 16163 Genova, Italy.
  • Zara F; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.
  • Galietta LJV; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, 16132 Genova, Italy.
  • Bocciardi R; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
  • Castellani C; Department of Translational Medical Sciences (DISMET), University of Naples Federico II, 80131 Naples, Italy.
  • Pedemonte N; UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.
Int J Mol Sci ; 23(6)2022 Mar 15.
Article en En | MEDLINE | ID: mdl-35328596
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Regulador de Conductancia de Transmembrana de Fibrosis Quística / Fibrosis Quística Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Italia
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Regulador de Conductancia de Transmembrana de Fibrosis Quística / Fibrosis Quística Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Italia