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Highly active CAR T cells that bind to a juxtamembrane region of mesothelin and are not blocked by shed mesothelin.
Liu, Xiufen; Onda, Masanori; Watson, Nathan; Hassan, Raffit; Ho, Mitchell; Bera, Tapan K; Wei, Junxia; Chakraborty, Anirban; Beers, Richard; Zhou, Qi; Shajahan, Asif; Azadi, Parastoo; Zhan, Jingyu; Xia, Di; Pastan, Ira.
Afiliación
  • Liu X; Laboratory of Molecular Biology, National Cancer Institute (NCI), Bethesda, MD 20892-4264.
  • Onda M; Laboratory of Molecular Biology, National Cancer Institute (NCI), Bethesda, MD 20892-4264.
  • Watson N; Laboratory of Molecular Biology, National Cancer Institute (NCI), Bethesda, MD 20892-4264.
  • Hassan R; Thoracic and GI Malignancies Branch, NCI, Bethesda, MD 20892.
  • Ho M; Laboratory of Molecular Biology, National Cancer Institute (NCI), Bethesda, MD 20892-4264.
  • Bera TK; Laboratory of Molecular Biology, National Cancer Institute (NCI), Bethesda, MD 20892-4264.
  • Wei J; Laboratory of Molecular Biology, National Cancer Institute (NCI), Bethesda, MD 20892-4264.
  • Chakraborty A; Laboratory of Molecular Biology, National Cancer Institute (NCI), Bethesda, MD 20892-4264.
  • Beers R; Laboratory of Molecular Biology, National Cancer Institute (NCI), Bethesda, MD 20892-4264.
  • Zhou Q; Laboratory of Molecular Biology, National Cancer Institute (NCI), Bethesda, MD 20892-4264.
  • Shajahan A; Analytical Services and Training, University of Georgia, Athens, GA 30602-4712.
  • Azadi P; Analytical Services and Training, University of Georgia, Athens, GA 30602-4712.
  • Zhan J; Laboratory of Cell Biology, NCI, Bethesda, MD 20892-4255.
  • Xia D; Laboratory of Cell Biology, NCI, Bethesda, MD 20892-4255.
  • Pastan I; Laboratory of Molecular Biology, National Cancer Institute (NCI), Bethesda, MD 20892-4264.
Proc Natl Acad Sci U S A ; 119(19): e2202439119, 2022 05 10.
Article en En | MEDLINE | ID: mdl-35512094

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Quiméricos de Antígenos Tipo de estudio: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Quiméricos de Antígenos Tipo de estudio: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article