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Synthesis of AC1903 analogs as potent transient receptor potential canonical channel 4/5 inhibitors and biological evaluation.
Chen, Lili; Zhang, Zhuang; Tian, Hongtao; Jiang, Shan; Ji, Yunyun; Liu, Mengru; Shen, Jianhua; Cao, Zhengyu; Wang, Kai.
Afiliación
  • Chen L; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences, No. 555 Zu Chong Zhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China.
  • Zhang Z; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of TCM Pharmacology, School of Traditional Chinese Pharmacy, China Pharmaceutical University, No. 639 Long Mian Road, Nanjing, Jiangsu 211198, China.
  • Tian H; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences, No. 555 Zu Chong Zhi Road, Shanghai 201203, China.
  • Jiang S; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of TCM Pharmacology, School of Traditional Chinese Pharmacy, China Pharmaceutical University, No. 639 Long Mian Road, Nanjing, Jiangsu 211198, China.
  • Ji Y; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of TCM Pharmacology, School of Traditional Chinese Pharmacy, China Pharmaceutical University, No. 639 Long Mian Road, Nanjing, Jiangsu 211198, China.
  • Liu M; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of TCM Pharmacology, School of Traditional Chinese Pharmacy, China Pharmaceutical University, No. 639 Long Mian Road, Nanjing, Jiangsu 211198, China.
  • Shen J; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences, No. 555 Zu Chong Zhi Road, Shanghai 201203, China.
  • Cao Z; Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of TCM Pharmacology, School of Traditional Chinese Pharmacy, China Pharmaceutical University, No. 639 Long Mian Road, Nanjing, Jiangsu 211198, China. Electronic address: zycao@cpu.edu.cn.
  • Wang K; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences, No. 555 Zu Chong Zhi Road, Shanghai 201203, China. Electronic address: kwang@simm.ac.cn.
Bioorg Med Chem ; 68: 116853, 2022 08 15.
Article en En | MEDLINE | ID: mdl-35653869
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Canales Catiónicos TRPC / Indazoles Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Canales Catiónicos TRPC / Indazoles Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: China