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Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function.
Carling, Phillippa J; Ryan, Brent J; McGuinness, William; Kataria, Shikha; Humble, Stewart W; Milde, Stefan; Duce, James A; Kapadia, Nirav; Zuercher, William J; Davis, John B; Di Daniel, Elena; Wade-Martins, Richard.
Afiliación
  • Carling PJ; Department of Physiology, Anatomy and Genetics, Oxford Parkinson's Disease Centre, University of Oxford, Oxford, UK.
  • Ryan BJ; Oxford Drug Discovery Institute, Target Discovery Institute, University of Oxford, NDM Research Building, Old Road Campus, Oxford, UK.
  • McGuinness W; Department of Physiology, Anatomy and Genetics, Oxford Parkinson's Disease Centre, University of Oxford, Oxford, UK.
  • Kataria S; Department of Physiology, Anatomy and Genetics, Oxford Parkinson's Disease Centre, University of Oxford, Oxford, UK.
  • Humble SW; Department of Physiology, Anatomy and Genetics, Oxford Parkinson's Disease Centre, University of Oxford, Oxford, UK.
  • Milde S; Oxford Drug Discovery Institute, Target Discovery Institute, University of Oxford, NDM Research Building, Old Road Campus, Oxford, UK.
  • Duce JA; Department of Physiology, Anatomy and Genetics, Oxford Parkinson's Disease Centre, University of Oxford, Oxford, UK.
  • Kapadia N; Inherited Neurodegenerative Diseases Unit, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD USA.
  • Zuercher WJ; ALBORADA Drug Discovery Institute, University of Cambridge, Island Research Building, Cambridge Biomedical Campus, Cambridge.
  • Davis JB; ALBORADA Drug Discovery Institute, University of Cambridge, Island Research Building, Cambridge Biomedical Campus, Cambridge.
  • Di Daniel E; Structural Genomics Consortium, UNC, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC USA.
  • Wade-Martins R; Structural Genomics Consortium, UNC, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC USA.
Autophagy ; 19(2): 692-705, 2023 02.
Article en En | MEDLINE | ID: mdl-35786165
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Autofagia / Factores de Transcripción Básicos con Cremalleras de Leucinas y Motivos Hélice-Asa-Hélice Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: En Revista: Autophagy Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Autofagia / Factores de Transcripción Básicos con Cremalleras de Leucinas y Motivos Hélice-Asa-Hélice Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: En Revista: Autophagy Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido