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A versatile fluorescence-quenched substrate for quantitative measurement of glucocerebrosidase activity within live cells.
Deen, Matthew C; Zhu, Yanping; Gros, Christina; Na, Na; Gilormini, Pierre-André; Shen, David L; Bhosale, Sandeep; Anastasi, Nadia; Wang, RuiQi; Shan, Xiaoyang; Harde, Eva; Jagasia, Ravi; Lynn, Francis C; Vocadlo, David J.
Afiliación
  • Deen MC; Department of Chemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
  • Zhu Y; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
  • Gros C; Department of Chemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
  • Na N; Department of Chemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
  • Gilormini PA; Department of Chemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
  • Shen DL; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
  • Bhosale S; Department of Chemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
  • Anastasi N; Department of Chemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
  • Wang R; Roche Pharma Research and Early Development, Neuroscience and Rare Diseases Discovery and Translational Area, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Shan X; Department of Chemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
  • Harde E; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
  • Jagasia R; Roche Pharma Research and Early Development, Neuroscience and Rare Diseases Discovery and Translational Area, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Lynn FC; Roche Pharma Research and Early Development, Neuroscience and Rare Diseases Discovery and Translational Area, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Vocadlo DJ; Diabetes Research Group, BC Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.
Proc Natl Acad Sci U S A ; 119(29): e2200553119, 2022 07 19.
Article en En | MEDLINE | ID: mdl-35858317
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Enfermedad de Gaucher / Glucosilceramidasa Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article País de afiliación: Canadá
Texto completo
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Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Enfermedad de Gaucher / Glucosilceramidasa Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article País de afiliación: Canadá