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Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis.
Ahangari, Farida; Becker, Christine; Foster, Daniel G; Chioccioli, Maurizio; Nelson, Meghan; Beke, Keriann; Wang, Xing; Justet, Aurelien; Adams, Taylor; Readhead, Benjamin; Meador, Carly; Correll, Kelly; Lili, Loukia N; Roybal, Helen M; Rose, Kadi-Ann; Ding, Shuizi; Barnthaler, Thomas; Briones, Natalie; DeIuliis, Giuseppe; Schupp, Jonas C; Li, Qin; Omote, Norihito; Aschner, Yael; Sharma, Lokesh; Kopf, Katrina W; Magnusson, Björn; Hicks, Ryan; Backmark, Anna; Dela Cruz, Charles S; Rosas, Ivan; Cousens, Leslie P; Dudley, Joel T; Kaminski, Naftali; Downey, Gregory P.
Afiliación
  • Ahangari F; Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
  • Becker C; Institute for Next Generation Healthcare, Department of Genetics and Genomic Sciences, and.
  • Foster DG; Division of Clinical Immunology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Chioccioli M; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Department of Pediatrics, and Department of Immunology and Genomic Medicine, National Jewish Health, Denver, Colorado.
  • Nelson M; Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
  • Beke K; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Department of Pediatrics, and Department of Immunology and Genomic Medicine, National Jewish Health, Denver, Colorado.
  • Wang X; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Department of Pediatrics, and Department of Immunology and Genomic Medicine, National Jewish Health, Denver, Colorado.
  • Justet A; Institute for Next Generation Healthcare, Department of Genetics and Genomic Sciences, and.
  • Adams T; Division of Clinical Immunology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Readhead B; Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
  • Meador C; Service de Pneumologie, UNICAEN, Normandie University, Caen, France.
  • Correll K; Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
  • Lili LN; Institute for Next Generation Healthcare, Department of Genetics and Genomic Sciences, and.
  • Roybal HM; ASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, Arizona.
  • Rose KA; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Department of Pediatrics, and Department of Immunology and Genomic Medicine, National Jewish Health, Denver, Colorado.
  • Ding S; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Department of Pediatrics, and Department of Immunology and Genomic Medicine, National Jewish Health, Denver, Colorado.
  • Barnthaler T; Institute for Next Generation Healthcare, Department of Genetics and Genomic Sciences, and.
  • Briones N; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Department of Pediatrics, and Department of Immunology and Genomic Medicine, National Jewish Health, Denver, Colorado.
  • DeIuliis G; Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
  • Schupp JC; Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
  • Li Q; Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
  • Omote N; Section of Pharmacology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria.
  • Aschner Y; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Department of Pediatrics, and Department of Immunology and Genomic Medicine, National Jewish Health, Denver, Colorado.
  • Sharma L; Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
  • Kopf KW; Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
  • Magnusson B; Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
  • Hicks R; Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
  • Backmark A; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Department of Pediatrics, and Department of Immunology and Genomic Medicine, National Jewish Health, Denver, Colorado.
  • Dela Cruz CS; Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
  • Rosas I; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Department of Pediatrics, and Department of Immunology and Genomic Medicine, National Jewish Health, Denver, Colorado.
  • Cousens LP; Discovery Biology, Discovery Sciences, Research & Development, AstraZeneca, Gothenburg, Sweden.
  • Dudley JT; BioPharmaceuticals Research & Development Cell Therapy, Research, and Early Development, Cardiovascular, Renal, and Metabolism (CVRM), AstraZeneca, Gothenburg, Sweden.
  • Kaminski N; Discovery Biology, Discovery Sciences, Research & Development, AstraZeneca, Gothenburg, Sweden.
  • Downey GP; Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
Am J Respir Crit Care Med ; 206(12): 1463-1479, 2022 12 15.
Article en En | MEDLINE | ID: mdl-35998281
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores de Proteínas Quinasas / Fibrosis Pulmonar Idiopática Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Am J Respir Crit Care Med Asunto de la revista: TERAPIA INTENSIVA Año: 2022 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores de Proteínas Quinasas / Fibrosis Pulmonar Idiopática Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Am J Respir Crit Care Med Asunto de la revista: TERAPIA INTENSIVA Año: 2022 Tipo del documento: Article