Resolution of inflammation via RvD1/FPR2 signaling mitigates Nox2 activation and ferroptosis of macrophages in experimental abdominal aortic aneurysms.

Filiberto, Amanda C; Ladd, Zachary; Leroy, Victoria; Su, Gang; Elder, Craig T; Pruitt, Eric Y; Hensley, Sara E; Lu, Guanyi; Hartman, Joseph B; Zarrinpar, Ali; Sharma, Ashish K; Upchurch, Gilbert R

Filiberto, Amanda C; Ladd, Zachary; Leroy, Victoria; Su, Gang; Elder, Craig T; Pruitt, Eric Y; Hensley, Sara E; Lu, Guanyi; Hartman, Joseph B; Zarrinpar, Ali; Sharma, Ashish K; Upchurch, Gilbert R.

Afiliación

Filiberto AC; Department of Surgery, University of Florida, Gainesville, Florida, USA.
Ladd Z; Department of Surgery, University of Florida, Gainesville, Florida, USA.
Leroy V; Department of Surgery, University of Florida, Gainesville, Florida, USA.
Su G; Department of Surgery, University of Florida, Gainesville, Florida, USA.
Elder CT; Department of Surgery, University of Florida, Gainesville, Florida, USA.
Pruitt EY; Department of Surgery, University of Florida, Gainesville, Florida, USA.
Hensley SE; Department of Surgery, University of Florida, Gainesville, Florida, USA.
Lu G; Department of Surgery, University of Florida, Gainesville, Florida, USA.
Hartman JB; Department of Surgery, University of Florida, Gainesville, Florida, USA.
Zarrinpar A; Department of Surgery, University of Florida, Gainesville, Florida, USA.
Sharma AK; Department of Surgery, University of Florida, Gainesville, Florida, USA.
Upchurch GR; Department of Surgery, University of Florida, Gainesville, Florida, USA.

FASEB J ; 36(11): e22579, 2022 11.

Article en En | MEDLINE | ID: mdl-36183323

Asunto(s)

Aneurisma de la Aorta Abdominal; Ferroptosis; Proteína HMGB1; Actinas/metabolismo; Animales; Aneurisma de la Aorta Abdominal/metabolismo; Citocinas/metabolismo; Modelos Animales de Enfermedad; Ácidos Docosahexaenoicos/metabolismo; Proteína HMGB1/metabolismo; Humanos; Inflamación/metabolismo; Macrófagos/metabolismo; Ratones; Ratones Endogámicos C57BL; Factor 2 Relacionado con NF-E2/metabolismo; Elastasa Pancreática/metabolismo; ARN Mensajero/metabolismo; Receptores de Formil Péptido/genética; Receptores de Formil Péptido/metabolismo; Receptores de Lipoxina; Remodelación Vascular

Palabras clave

HMGB1; abdominal aortic aneurysms; ferroptosis; formyl peptide receptor 2; macrophages; resolvin D1

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Aneurisma de la Aorta Abdominal / Proteína HMGB1 / Ferroptosis Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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