Acute myotonic reaction during succinylcholine anaesthesia.
Pract Neurol
; 23(1): 74-77, 2023 Feb.
Article
en En
| MEDLINE
| ID: mdl-36192135
ABSTRACT
A 21-year-old woman developed an acute myotonic reaction while undergoing anaesthesia using succinylcholine. Examination later showed she had shoulder, neck and calf hypertrophy, bilateral symmetrical ptosis and eyelid, handgrip and percussion myotonia. Peripheral neurophysiology studies identified significant, continuous myotonic discharges in both upper and lower limbs. Genetic analysis identified a c.3917G>A (p.Gly1306Glu) mutation in the SCN4A gene, confirming a diagnosis of sodium channel myotonia. Succinylcholine and other depolarising agents can precipitate life-threatening acute myotonic reactions when given to patients with myotonia. Patients with neuromuscular disorders are at an increased risk of perioperative anaesthetic complications. We report a woman who developed an acute myotonic reaction whilst undergoing anaesthesia, in the context of an unrecognised myotonic disorder. We then discuss an approach to the diagnosis of myotonic disorders.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Trastornos Miotónicos
/
Anestesia
/
Miotonía
Límite:
Adult
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Female
/
Humans
Idioma:
En
Revista:
Pract Neurol
Año:
2023
Tipo del documento:
Article
País de afiliación:
Trinidad y Tobago