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NPP-669, a Novel Broad-Spectrum Antiviral Therapeutic with Excellent Cellular Uptake, Antiviral Potency, Oral Bioavailability, Preclinical Efficacy, and a Promising Safety Margin.
Lipka, Elke; Chadderdon, Aaron M; Harteg, Cheryl C; Doherty, Matthew K; Simon, Eric S; Domagala, John M; Reyna, Dawn M; Hutchings, Kim M; Gan, Xinmin; White, Andrew D; Hartline, Caroll B; Harden, Emma A; Keith, Kathy A; Prichard, Mark N; James, Scott H; Cardin, Rhonda D; Bernstein, David I; Spencer, Jacqueline F; Tollefson, Ann E; Wold, William S M; Toth, Karoly.
Afiliación
  • Lipka E; TSRL, Inc., 540 Avis Dr., Suite A, Ann Arbor, Michigan 48108, United States.
  • Chadderdon AM; TSRL, Inc., 540 Avis Dr., Suite A, Ann Arbor, Michigan 48108, United States.
  • Harteg CC; TSRL, Inc., 540 Avis Dr., Suite A, Ann Arbor, Michigan 48108, United States.
  • Doherty MK; TSRL, Inc., 540 Avis Dr., Suite A, Ann Arbor, Michigan 48108, United States.
  • Simon ES; TSRL, Inc., 540 Avis Dr., Suite A, Ann Arbor, Michigan 48108, United States.
  • Domagala JM; TSRL, Inc., 540 Avis Dr., Suite A, Ann Arbor, Michigan 48108, United States.
  • Reyna DM; TSRL, Inc., 540 Avis Dr., Suite A, Ann Arbor, Michigan 48108, United States.
  • Hutchings KM; College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Gan X; College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • White AD; College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States.
  • Hartline CB; Department of Pediatrics, University of Alabama School of Medicine, Birmingham, Alabama 35233, United States.
  • Harden EA; Department of Pediatrics, University of Alabama School of Medicine, Birmingham, Alabama 35233, United States.
  • Keith KA; Department of Pediatrics, University of Alabama School of Medicine, Birmingham, Alabama 35233, United States.
  • Prichard MN; Department of Pediatrics, University of Alabama School of Medicine, Birmingham, Alabama 35233, United States.
  • James SH; Department of Pediatrics, University of Alabama School of Medicine, Birmingham, Alabama 35233, United States.
  • Cardin RD; School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana 70803, United States.
  • Bernstein DI; Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio 45229, United States.
  • Spencer JF; Saint Louis University School of Medicine, St. Louis, Missouri 63104, United States.
  • Tollefson AE; Saint Louis University School of Medicine, St. Louis, Missouri 63104, United States.
  • Wold WSM; Saint Louis University School of Medicine, St. Louis, Missouri 63104, United States.
  • Toth K; Saint Louis University School of Medicine, St. Louis, Missouri 63104, United States.
Mol Pharm ; 20(1): 370-382, 2023 01 02.
Article en En | MEDLINE | ID: mdl-36484496
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Profármacos / Infecciones por Citomegalovirus / Organofosfonatos Límite: Animals / Humans Idioma: En Revista: Mol Pharm Asunto de la revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Profármacos / Infecciones por Citomegalovirus / Organofosfonatos Límite: Animals / Humans Idioma: En Revista: Mol Pharm Asunto de la revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos