Periostin promotes ovarian cancer metastasis by enhancing M2 macrophages and cancer-associated fibroblasts via integrin-mediated NF-&#954;B and TGF-ß2 signaling.

Lin, Sheng-Chieh; Liao, Yi-Chu; Chen, Po-Ming; Yang, Ya-Yu; Wang, Yi-Hsiang; Tung, Shiao-Lin; Chuang, Chi-Mu; Sung, Yu-Wen; Jang, Te-Hsuan; Chuang, Shuang-En; Wang, Lu-Hai

Periostin promotes ovarian cancer metastasis by enhancing M2 macrophages and cancer-associated fibroblasts via integrin-mediated NF-κB and TGF-ß2 signaling.

Lin, Sheng-Chieh; Liao, Yi-Chu; Chen, Po-Ming; Yang, Ya-Yu; Wang, Yi-Hsiang; Tung, Shiao-Lin; Chuang, Chi-Mu; Sung, Yu-Wen; Jang, Te-Hsuan; Chuang, Shuang-En; Wang, Lu-Hai.

Afiliación

Lin SC; Graduate Institute of Integrated Medicine and Chinese Medicine Research Center, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan.
Liao YC; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.
Chen PM; Institute of Molecular and Genomic Medicine, National Health Research Institutes, Miaoli, Taiwan.
Yang YY; Graduate Institute of Integrated Medicine and Chinese Medicine Research Center, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan.
Wang YH; Research Assistant Center, Show Chwan Memorial Hospital, Changhua, Taiwan.
Tung SL; National Institute of Cancer Research, National Health Research Institutes, Miaoli, Taiwan.
Chuang CM; Institute of Molecular and Genomic Medicine, National Health Research Institutes, Miaoli, Taiwan.
Sung YW; Institute of Molecular Medicine, National Tsing Hua University, Hsinchu, Taiwan.
Jang TH; Department of Hematology and Oncology, Ton-Yen General Hospital, Hsinchu, Taiwan.
Chuang SE; Department of Nursing, Hsin Sheng Junior College of Medical Care and Management, Taoyuan, Taiwan.
Wang LH; Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan.

J Biomed Sci ; 29(1): 109, 2022 Dec 22.

Article en En | MEDLINE | ID: mdl-36550569

Asunto(s)

Fibroblastos Asociados al Cáncer; Neoplasias Ováricas; Femenino; Humanos; FN-kappa B/genética; FN-kappa B/metabolismo; Fibroblastos Asociados al Cáncer/metabolismo; Integrinas/metabolismo; Factor de Crecimiento Transformador beta2/metabolismo; Línea Celular Tumoral; Neoplasias Ováricas/genética; Citocinas/metabolismo; Macrófagos/metabolismo; Microambiente Tumoral/genética

Palabras clave

Cancer-associated fibroblast; Macrophages; Metastasis; NF-κB; Ovarian cancer; Periostin; TGF-ß2

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Fibroblastos Asociados al Cáncer Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: J Biomed Sci Asunto de la revista: MEDICINA Año: 2022 Tipo del documento: Article País de afiliación: Taiwán

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