Mechanochemical Rules for Shape-Shifting Filaments that Remodel Membranes.
Phys Rev Lett
; 129(26): 268101, 2022 Dec 23.
Article
en En
| MEDLINE
| ID: mdl-36608212
ABSTRACT
The sequential exchange of filament composition to increase filament curvature was proposed as a mechanism for how some biological polymers deform and cut membranes. The relationship between the filament composition and its mechanical effect is lacking. We develop a kinetic model for the assembly of composite filaments that includes protein-membrane adhesion, filament mechanics and membrane mechanics. We identify the physical conditions for such a membrane remodeling and show this mechanism of sequential polymer assembly lowers the energetic barrier for membrane deformation.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Polímeros
/
Citoesqueleto
Idioma:
En
Revista:
Phys Rev Lett
Año:
2022
Tipo del documento:
Article
País de afiliación:
Austria