The role of FUT8-catalyzed core fucosylation in Alzheimer's amyloid-ß oligomer-induced activation of human microglia.

Jin, Lee-Way; di Lucente, Jacopo; Ruiz Mendiola, Ulises; Tang, Xinyu; Zivkovic, Angela M; Lebrilla, Carlito B; Maezawa, Izumi

Jin, Lee-Way; di Lucente, Jacopo; Ruiz Mendiola, Ulises; Tang, Xinyu; Zivkovic, Angela M; Lebrilla, Carlito B; Maezawa, Izumi.

Afiliación

Jin LW; Department of Pathology and Laboratory Medicine and M.I.N.D. Institute, University of California Davis Medical Center, Sacramento, California, USA.
di Lucente J; Department of Pathology and Laboratory Medicine and M.I.N.D. Institute, University of California Davis Medical Center, Sacramento, California, USA.
Ruiz Mendiola U; Department of Pathology and Laboratory Medicine and M.I.N.D. Institute, University of California Davis Medical Center, Sacramento, California, USA.
Tang X; Department of Nutrition, University of California, Davis, California, USA.
Zivkovic AM; Department of Nutrition, University of California, Davis, California, USA.
Lebrilla CB; Department of Chemistry, University of California, Davis, California, USA.
Maezawa I; Department of Pathology and Laboratory Medicine and M.I.N.D. Institute, University of California Davis Medical Center, Sacramento, California, USA.

Glia ; 71(5): 1346-1359, 2023 05.

Article en En | MEDLINE | ID: mdl-36692036

Asunto(s)

Enfermedad de Alzheimer; Células Madre Pluripotentes Inducidas; Humanos; Ratones; Animales; Fucosiltransferasas/metabolismo; Microglía/metabolismo; Péptidos beta-Amiloides/metabolismo; Enfermedad de Alzheimer/metabolismo; Proteína p53 Supresora de Tumor; Células Madre Pluripotentes Inducidas/metabolismo; Citocinas/metabolismo; Catálisis

Palabras clave

Alzheimer's; amyloid; fucosylation; fucosyltransferase; glycosylation; microglia; p53

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas / Enfermedad de Alzheimer Límite: Animals / Humans Idioma: En Revista: Glia Asunto de la revista: NEUROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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