Simultaneous and sequential combination of genetic and epigenetic biomarkers for the presence of high-grade dysplasia in patients with pancreatic cyst: Discovery in cyst fluid and test in pancreatic juice.

Hata, Tatsuo; Mizuma, Masamichi; Kusakabe, Takashi; Amano, Hodaka; Furukawa, Toru; Iwao, Toshiyasu; Unno, Michiaki

Hata, Tatsuo; Mizuma, Masamichi; Kusakabe, Takashi; Amano, Hodaka; Furukawa, Toru; Iwao, Toshiyasu; Unno, Michiaki.

Afiliación

Hata T; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan; Department of Surgery, Aidu Chuo Hospital, Aizuwakamatsu, Japan. Electronic address: hatata@surg.med.tohoku.ac.jp.
Mizuma M; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kusakabe T; Department of Pathology, Aidu Chuo Hospital, Aizuwakamatsu, Japan.
Amano H; Department of Surgery, Aidu Chuo Hospital, Aizuwakamatsu, Japan.
Furukawa T; Department of Investigative Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Iwao T; Department of Gastroenterology, Aidu Chuo Hospital, Aizuwakamatsu, Japan.
Unno M; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.

Pancreatology ; 23(2): 218-226, 2023 Mar.

Article en En | MEDLINE | ID: mdl-36707261

Asunto(s)

Carcinoma Ductal Pancreático; Quiste Pancreático; Neoplasias Intraductales Pancreáticas; Neoplasias Pancreáticas; Humanos; Carcinoma Ductal Pancreático/patología; Líquido Quístico/química; Jugo Pancreático/química; Proteínas Proto-Oncogénicas p21(ras)/genética; Neoplasias Pancreáticas/patología; Biomarcadores/análisis; Quiste Pancreático/diagnóstico; Epigénesis Genética; Biomarcadores de Tumor/análisis; Proteínas de Dominio T Box/genética

Palabras clave

Droplet digital PCR; Grade of dysplasia; Intraductal papillary mucinous neoplasm of the pancreas; Methylation; Serial pancreatic juice aspiration cytological examination

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quiste Pancreático / Neoplasias Pancreáticas / Carcinoma Ductal Pancreático / Neoplasias Intraductales Pancreáticas Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Pancreatology Asunto de la revista: ENDOCRINOLOGIA / GASTROENTEROLOGIA Año: 2023 Tipo del documento: Article

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