Structures of NF-&#954;B p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation.

Pan, Wenfei; Meshcheryakov, Vladimir A; Li, Tianjie; Wang, Yi; Ghosh, Gourisankar; Wang, Vivien Ya-Fan

Structures of NF-κB p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation.

Pan, Wenfei; Meshcheryakov, Vladimir A; Li, Tianjie; Wang, Yi; Ghosh, Gourisankar; Wang, Vivien Ya-Fan.

Afiliación

Pan W; Faculty of Health Sciences, University of Macau, Taipa, China.
Meshcheryakov VA; Faculty of Health Sciences, University of Macau, Taipa, China.
Li T; Department of Physics, Chinese University of Hong Kong, Shatin, Hong Kong.
Wang Y; Department of Physics, Chinese University of Hong Kong, Shatin, Hong Kong.
Ghosh G; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, United States.
Wang VY; Faculty of Health Sciences, University of Macau, Taipa, China.

Elife ; 122023 02 13.

Article en En | MEDLINE | ID: mdl-36779700

Asunto(s)

Subunidad p52 de NF-kappa B; FN-kappa B; Animales; Humanos; ADN/metabolismo; Mamíferos/metabolismo; FN-kappa B/metabolismo; Subunidad p52 de NF-kappa B/química; Activación Transcripcional; Multimerización de Proteína

Palabras clave

DNA conformation; E. coli; MD simulation; NF-κB; biochemistry; chemical biology; crystal structure; kinetics; molecular biophysics; structural biology; thermodynamics; transcriptional regulation

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: FN-kappa B / Subunidad p52 de NF-kappa B Límite: Animals / Humans Idioma: En Revista: Elife Año: 2023 Tipo del documento: Article País de afiliación: China

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