Differential role for rapid proteostasis in Rho GTPase-mediated control of quiescent endothelial integrity.

Podieh, Fabienne; Wensveen, Roos; Overboom, Max C; Abbas, Lotte; Majolée, Jisca; Hordijk, Peter L

Podieh, Fabienne; Wensveen, Roos; Overboom, Max C; Abbas, Lotte; Majolée, Jisca; Hordijk, Peter L.

Afiliación

Podieh F; Amsterdam UMC, Location Vrije Universiteit Amsterdam, Physiology, Amsterdam, The Netherlands; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, The Netherlands.
Wensveen R; Amsterdam UMC, Location Vrije Universiteit Amsterdam, Physiology, Amsterdam, The Netherlands; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, The Netherlands.
Overboom MC; Amsterdam UMC, Location Vrije Universiteit Amsterdam, Physiology, Amsterdam, The Netherlands; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, The Netherlands.
Abbas L; Amsterdam UMC, Location Vrije Universiteit Amsterdam, Physiology, Amsterdam, The Netherlands; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, The Netherlands.
Majolée J; Amsterdam UMC, Location Vrije Universiteit Amsterdam, Physiology, Amsterdam, The Netherlands; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, The Netherlands; Developmental Biology and Stem Cell Research, Hubrecht Institute, Utrecht, The Netherlands.
Hordijk PL; Amsterdam UMC, Location Vrije Universiteit Amsterdam, Physiology, Amsterdam, The Netherlands; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, The Netherlands. Electronic address: p.hordijk@amsterdamumc.nl.

J Biol Chem ; 299(4): 104593, 2023 04.

Article en En | MEDLINE | ID: mdl-36894017

Asunto(s)

Actinas; Proteínas de Unión al GTP rho; Humanos; Proteínas de Unión al GTP rho/genética; Proteínas de Unión al GTP rho/metabolismo; Actinas/metabolismo; Células Endoteliales/metabolismo; Proteostasis; Proteína de Unión al GTP rhoA/metabolismo; Endotelio Vascular/metabolismo; Células Cultivadas

Palabras clave

Rho GTPases; endothelial cells; monolayer integrity; proteostasis; ubiquitin

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Actinas / Proteínas de Unión al GTP rho Límite: Humans Idioma: En Revista: J Biol Chem Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos

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