A Single Active-Site Mutagenesis Confers Enhanced Activity and/or Changed Product Distribution to a Pentalenene Synthase from <i>Streptomyces</i> sp. PSKA01.

Liu, Hongshuang; Fang, Senbiao; Zhao, Lin; Men, Xiao; Zhang, Haibo

A Single Active-Site Mutagenesis Confers Enhanced Activity and/or Changed Product Distribution to a Pentalenene Synthase from Streptomyces sp. PSKA01.

Liu, Hongshuang; Fang, Senbiao; Zhao, Lin; Men, Xiao; Zhang, Haibo.

Afiliación

Liu H; State Key Laboratory of Bio-Based Material and Green Papermaking, School of Bioengineering, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250316, China.
Fang S; CAS Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China.
Zhao L; CAS Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China.
Men X; Shandong Energy Institute, Qingdao 266101, China.
Zhang H; State Key Laboratory of Bio-Based Material and Green Papermaking, School of Bioengineering, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250316, China.

Bioengineering (Basel) ; 10(3)2023 Mar 22.

Article en En | MEDLINE | ID: mdl-36978783

Palabras clave

molecular docking; molecular dynamics simulations; pentalenene; pentalenene synthase; random mutagenesis; site-saturation mutagenesis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Bioengineering (Basel) Año: 2023 Tipo del documento: Article País de afiliación: China

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