Basis for the discrimination of supercoil handedness during DNA cleavage by human and bacterial type II topoisomerases.

Jian, Jeffrey Y; McCarty, Kevin D; Byl, Jo Ann W; Guengerich, F Peter; Neuman, Keir C; Osheroff, Neil

Jian, Jeffrey Y; McCarty, Kevin D; Byl, Jo Ann W; Guengerich, F Peter; Neuman, Keir C; Osheroff, Neil.

Afiliación

Jian JY; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
McCarty KD; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Byl JAW; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Guengerich FP; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Neuman KC; Laboratory of Single Molecule Biophysics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20982, USA.
Osheroff N; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

Nucleic Acids Res ; 51(8): 3888-3902, 2023 05 08.

Article en En | MEDLINE | ID: mdl-36999602

Asunto(s)

Antineoplásicos; Topoisomerasa de ADN IV; Humanos; Topoisomerasa de ADN IV/genética; ADN Superhelicoidal; División del ADN; Lateralidad Funcional; ADN-Topoisomerasas de Tipo II/genética; ADN

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Topoisomerasa de ADN IV / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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